SCHEMBL373739

SCHEMBL373739

C=Cc1ccccc1[Si](C)(C)O[Si](C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL373306 0.91 ALDH1A1 (0.34) ALDH1A1
SCHEMBL373779 0.91 ALDH1A1 (0.34) ALDH1A1
SCHEMBL373401 0.90 ALDH1A1 (0.33) ALDH1A1
SCHEMBL373533 0.90 ALDH1A1 (0.33) ALDH1A1
SCHEMBL372833 0.90 ALDH1A1 (0.33) ALDH1A1
SCHEMBL373818 0.90 ALDH1A1 (0.33) ALDH1A1
SCHEMBL373565 0.90 ALDH1A1 (0.33) ALDH1A1
SCHEMBL373429 0.85 ALDH1A1 (0.38) ALDH1A1
SCHEMBL441041 0.85 ALDH1A1 (0.38) ALDH1A1
SCHEMBL30862129 0.85 ALDH1A1 (0.38) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0770888-B1 Low water-absorptive ocular lens material, low water-absorptive ocular lens shaped product made thereof, low water-absorptive ocular lens made thereof and process for its production MENICON CO LTD (JP) 2004-08-04 EP claimed
EP-0600269-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1994-06-08 EP claimed
US-12428390-B2 Chromene compound and photochromic optical article TOKUYAMA CORPORATION (JP) 2025-09-30 US disclosed
EP-3822296-B1 POLYMER MATERIAL MENICON CO LTD (JP) 2025-09-10 EP disclosed
WO-2025094241-A1 COMPOSITE MEMBRANE 株式会社メニコン 2025-05-08 WO disclosed
US-20250115701-A1 POLYMER MATERIAL MENICON CO., LTD. (JP) 2025-04-10 US disclosed
US-12209154-B2 Polymer material MENICON CO., LTD. (JP) 2025-01-28 US disclosed
EP-3995493-B1 CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE TOKUYAMA CORP (JP) 2024-07-03 EP disclosed
US-20240026145-A1 OPHTHALMIC LENS MENICON CO., LTD. (JP) 2024-01-25 US disclosed
US-20240010777-A1 SURFACE TREATMENT AGENT FOR OPHTHALMIC DEVICE NOF CORPORATION (JP) 2024-01-11 US disclosed
EP-4258042-A1 SURFACE TREATMENT AGENT FOR OPHTHALMIC DEVICE NOF Corporation (JP) 2023-10-11 EP disclosed
EP-0381005-B1 Ocular lens material MENICON CO LTD (JP) 1995-01-11 EP disclosed
US-5346946-A Polysiloxane macromonomer MENICON CO., LTD (JP) 1994-09-13 US disclosed
EP-0600269-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1994-06-08 EP disclosed
EP-0584826-A2 Ocular lens material Menicon Co., Ltd. (JP) 1994-03-02 EP disclosed
EP-0584764-A1 Ocular lens material Menicon Co., Ltd. (JP) 1994-03-02 EP disclosed
EP-0578087-A2 Ocular lens material Menicon Co., Ltd. (JP) 1994-01-12 EP disclosed
US-5041511-A Vinyl benzene acrylate or methacrylate crosslinking agent MENICON CO., LTD. (JP) 1991-08-20 US disclosed
EP-0381005-A2 Ocular lens material Menicon Co., Ltd. (JP) 1990-08-08 EP disclosed
US-4594401-A Oxygen permeable hard contact lens formed from styrene monomer containing a silyl or siloxane group SHIN-ETSU CHEMICAL CO., LTD. (JP) 1986-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12428390-B2 Chromene compound and photochromic optical article CRY1, CRY2, RAD51 ALDH1A1 736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.