SCHEMBL3738153

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30197568	0.87	ALDH1A1 (0.49)	CYP2D6MAPTRECQLPKMALDH1A1
	SCHEMBL22283827	0.84	TSHR (0.57)	CYP2D6HTR2AHTR2CMAPTALDH1A1
	N-Methyl Pyrrolidine (Nmp) SCHEMBL29261751	0.84	CYP2D6 (0.60)	CYP2D6KMT2AHTR2AHTR2CMAPT
	N-Methyl Pyrrolidine (Nmp) SCHEMBL15994943	0.84	CYP2D6 (0.60)	CYP2D6KMT2AHTR2AHTR2CMAPT
	SCHEMBL3746565	0.83	NPC1 (0.46)	CYP2D6KMT2AMAPTRECQLPKM
	N-Methylpiperidine SCHEMBL2149763	0.82	CYP2D6 (0.59)	CYP2D6KMT2AHTR2AHTR2CMAPT
	Cyclohexanone SCHEMBL669721	0.82	ALDH1A1 (0.45)	CYP2D6KMT2AMAPTRECQLPKM
	SCHEMBL3728472	0.82	KMT2A (0.45)	CYP2D6KMT2AMAPTRECQLPKM
	SCHEMBL3728619	0.82	LMNA (0.56)	CYP2D6KMT2AMAPTRECQLPKM
	SCHEMBL3734356	0.81	CYP2D6 (0.48)	CYP2D6KMT2AHTR2AHTR2CMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.