Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5838258 | 0.85 | TSHR (0.39) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL10430815 | 0.81 | TSHR (0.37) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL3746493 | 0.81 | TSHR (0.37) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL1603671 | 0.81 | TSHR (0.37) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL3738182 | 0.81 | TSHR (0.37) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL3738193 | 0.81 | TSHR (0.37) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL18918481 | 0.81 | TSHR (0.37) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL11220689 | 0.81 | TSHR (0.39) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL1067359 | 0.80 | TSHR (0.36) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL16666960 | 0.80 | TSHR (0.36) | TSHRHPGDTHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834120-B2 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-1645560-B1 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHINETSU CHEMICAL CO (JP) | 2008-05-28 | — | — | EP | disclosed |
| EP-1645560-A1 | Monofunctional monomer having cage oligosiloxane structure and method of making | Shin-Etsu Chemical Co., Ltd. (JP) | 2006-04-12 | — | — | EP | disclosed |
| US-20060074213-A1 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-04-06 | — | — | US | disclosed |