SCHEMBL373869

SCHEMBL373869

CCC(=O)Oc1c(C(C)(C)C)cc(CCCCCCc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc1C(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 11/20 0.51
GAA P10253 4/20 0.47
KMT2A Q03164 2/20 0.46
LMNA P02545 2/20 0.42
RECQL P46063 1/20 0.42
ALDH1A1 P00352 2/20 0.40
TSHR P16473 2/20 0.40
MEN1 O00255 1/20 0.40
USP2 O75604 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
BLM P54132 1/20 0.40
ATM Q13315 1/20 0.40
HIF1A Q16665 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HMGCR P04035 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6131287 0.90 GPR84 (0.43) VCAM1CYP3A4
SCHEMBL10951961 0.83 GAA (0.47) GAAKMT2ALMNARECQLALDH1A1
Propionic Acid SCHEMBL31435015 0.82 GAA (0.54) GAAKMT2ALMNARECQLALDH1A1
SCHEMBL11134057 0.80 VCAM1 (0.57) VCAM1GAAKMT2AMEN1
SCHEMBL17588977 0.80 ALDH1A1 (0.57) GAAKMT2ALMNAALDH1A1TSHR
SCHEMBL18193748 0.80 ALDH1A1 (0.57) GAAKMT2ALMNAALDH1A1TSHR
SCHEMBL3762751 0.80 ALDH1A1 (0.57) GAAKMT2ALMNAALDH1A1TSHR
SCHEMBL8751548 0.80 ALDH1A1 (0.57) GAAKMT2ALMNAALDH1A1TSHR
SCHEMBL18193749 0.80 ALDH1A1 (0.57) GAAKMT2ALMNAALDH1A1TSHR
SCHEMBL8751503 0.80 ALDH1A1 (0.57) GAAKMT2ALMNAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4172268-B1 CHEMICALLY-RESISTANT FLAME RETARDANT COMPOSITIONS SHPP GLOBAL TECH BV (NL) 2024-07-03 EP disclosed
WO-2024002644-A1 METAL COMPLEXED CYANURATE GERMICIDAL ADDITIVE FOR POLYMER COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-01-04 WO disclosed
US-20230323110-A1 CHEMICALLY-RESISTANT FLAME RETARDANT COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-10-12 US disclosed
US-11745477-B2 Polyolefin based multilayer film with a hybrid barrier layer SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-09-05 US disclosed
US-20230242751-A1 SCRATCH-RESISTANT HIGH IMPACT STRENGTH PMMA COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-08-03 US disclosed
EP-3863850-B1 POLYOLEFIN BASED MULTILAYER FILM WITH A HYBRID BARRIER LAYER SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-06-28 EP disclosed
US-20210379874-A1 POLYOLEFIN BASED MULTILAYER FILM WITH A HYBRID BARRIER LAYER SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-12-09 US disclosed
US-20200255642-A1 STABILIZED FIBER-CONTAINING COMPOSITE FIBRE REINFORCED THERMOPLASTICS B.V. (NL) 2020-08-13 US disclosed
EP-2906621-B1 HETEROPHASIC POLYPROPYLENE COMPOSITION ABU DHABI POLYMERS CO LTD BOROUGE LLC (AE) 2020-07-29 EP disclosed
EP-3643493-A1 CO-POLYCARBONATE RESIN MATERIALS AND MATERIALS MADE THEREFROM SABIC Global Technologies B.V. (NL) 2020-04-29 EP disclosed
EP-2386602-A1 Automotive interior compound Borealis AG (AT) 2011-11-16 EP disclosed
EP-2240542-B1 LOW-STICKY ADDITIVE PACKAGE FOR AUTOMOTIVE INTERIOR APPLICATIONS BOREALIS AG (AT) 2011-06-15 EP disclosed
EP-2141197-B1 Polypropylene composition with improved properties BOREALIS AG (AT) 2011-05-25 EP disclosed
US-20110118396-A1 REDUCTION OF VOLATILES OF STABILIZED POLYPROPYLENE/TALC COMPOSITIONS BY USING SPECIFIC ACIDIC ENVIRONMENT BOREALIS AG (AT) 2011-05-19 US disclosed
US-20100286310-A1 LOW-STICKY ADDITIVE PACKAGE FOR AUTOMOTIVE INTERIOR APPLICATIONS BOREALIS AG (AT) 2010-11-11 US disclosed
EP-2141196-B1 Reduction of volatiles of stabilized polypropylene/talc compositions by using specific absorbers BOREALIS AG (AT) 2010-06-23 EP disclosed
EP-2141193-B1 Reduction of volatiles of stabilized polypropylene/talc compositions by using specific acidic environment BOREALIS AG (AT) 2010-04-28 EP disclosed
EP-2141193-A1 Reduction of volatiles of stabilized polypropylene/talc compositions by using specific acidic environment Borealis AG (AT) 2010-01-06 EP disclosed
EP-2141196-A1 Reduction of volatiles of stabilized polypropylene/talc compositions by using specific absorbers Borealis AG (AT) 2010-01-06 EP disclosed
EP-2141197-A1 Polypropylene composition with improved properties Borealis AG (AT) 2010-01-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118396-A1 REDUCTION OF VOLATILES OF STABILIZED POLYPROPYLENE/TALC COMPOSITIONS BY USING SPECIFIC ACIDIC ENVIRONMENT PPARA, VDAC1, BAX VCAM1 411/4885GAA 3304/4885KMT2A 2666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.