Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991255 | 0.98 | GPR84 (0.58) | GPR84LMNAFFAR1FFAR4PPARD | |
| SCHEMBL5171531 | 0.98 | GPR84 (0.58) | GPR84LMNAFFAR1FFAR4PPARD | |
| SCHEMBL28834415 | 0.94 | GPR84 (0.47) | GPR84LMNAFFAR1FFAR4PPARD | |
| SCHEMBL5203381 | 0.92 | GPR84 (0.55) | GPR84LMNAFFAR1FFAR4PPARD | |
| Ethylene Glycol SCHEMBL5137218 | 0.92 | GPR84 (0.60) | GPR84LMNAFFAR1FFAR4PPARD | |
| Ethylene Glycol SCHEMBL5137927 | 0.92 | GPR84 (0.60) | GPR84LMNAFFAR1FFAR4PPARD | |
| Ethylene Glycol SCHEMBL5136577 | 0.92 | GPR84 (0.60) | GPR84LMNAFFAR1FFAR4PPARD | |
| Ethylene Glycol SCHEMBL5138346 | 0.92 | GPR84 (0.60) | GPR84LMNAFFAR1FFAR4PPARD | |
| SCHEMBL4597758 | 0.92 | GPR84 (0.63) | GPR84LMNAFFAR1FFAR4PPARD | |
| SCHEMBL7202803 | 0.90 | GPR84 (0.58) | GPR84LMNAFFAR1FFAR4PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111351867-B | Analysis method for determining substances related to lubiprostone test sample | 南京正大天晴制药有限公司 | 2021-06-29 | — | — | CN | claimed |
| WO-2020125027-A1 | ANALYSIS METHOD FOR DETERMINING SUBSTANCE RELATED TO LUBIPROSTONE TEST SAMPLE | 南京正大天晴制药有限公司 | 2020-06-25 | — | — | WO | claimed |
| CN-103739481-A | Method for splitting naproxen employing chiral stationary phase | UNIV MINNAN NORMAL | 2014-04-23 | — | — | CN | claimed |
| CN-115047127-B | Method for identifying NFC and FC orange juice by utilizing volatile metabonomics technology | 中国检验检疫科学研究院 | 2024-03-08 | — | — | CN | disclosed |
| CN-111351867-B | Analysis method for determining substances related to lubiprostone test sample | 南京正大天晴制药有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-111351867-A | Analysis method for determining substances related to lubiprostone test sample | 南京正大天晴制药有限公司 | 2020-06-30 | — | — | CN | disclosed |
| WO-2020125027-A1 | ANALYSIS METHOD FOR DETERMINING SUBSTANCE RELATED TO LUBIPROSTONE TEST SAMPLE | 南京正大天晴制药有限公司 | 2020-06-25 | — | — | WO | disclosed |
| US-8901319-B2 | Process for the preparation of F-series prostaglandins | CAYMAN CHEMICAL COMPANY, INCORPORATED (US) | 2014-12-02 | — | — | US | disclosed |
| CN-103739481-A | Method for splitting naproxen employing chiral stationary phase | UNIV MINNAN NORMAL | 2014-04-23 | — | — | CN | disclosed |
| US-20120295004-A1 | CRYSTALS OF NON-NATURAL-TYPE STEREOISOMER SALT OF MONATIN AND USE THEREOF | AJINOMOTO CO., INC. (JP) | 2012-11-22 | — | — | US | disclosed |
| US-20120283451-A1 | PROCESS FOR THE PREPARATION OF F-SERIES PROSTAGLANDINS | CAYMAN CHEMICAL COMPANY, INCORPORATED | 2012-11-08 | — | — | US | disclosed |
| US-20020002274-A1 | Process for the production of perbenzylated 1-0-glycosides | SCHERING AKTIENGESELLSCHAFT | 2002-01-03 | — | — | US | disclosed |
| EP-0778269-B1 | PROSTAGLANDINS AND PROCESS FOR PRODUCING THE SAME | TEIJIN LTD (JP) | 2000-09-27 | — | — | EP | disclosed |
| US-5990346-A | AN INHIBITORS OF CELL MIGRATION CAUSED BY CHEMOKINES | TEIJIN LIMITED (JP) | 1999-11-23 | — | — | US | disclosed |
| US-5760238-A | ANTIISCHEMIC AGENTS | MERCIAN CORPORATION (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0779277-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVE | MERCIAN CORPORATION (JP) | 1997-06-18 | — | — | EP | disclosed |
| EP-0778269-A1 | PROSTAGLANDINS AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1997-06-11 | — | — | EP | disclosed |
| EP-0003583-B1 | COMPOSITIONS FOR CYTOCHEMICAL INVESTIGATION, THEIR USE AND METHOD FOR THE DETECTION OF STEROID HORMONE RECEPTORS IN HUMAN TISSUES | Lee, Sin Hang (US) | 1981-12-02 | — | — | EP | disclosed |
| US-4204001-A | PROSTAGLANDINS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-05-20 | — | — | US | disclosed |
| US-4115580-A | PROSTAGLANDINS, LUTEOLYSIS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295004-A1 | CRYSTALS OF NON-NATURAL-TYPE STEREOISOMER SALT OF MONATIN AND USE THEREOF | MON2, SRI, CROCC | GPR84 1148/4885LMNA 2825/4885FFAR1 1545/4885 |
| US-20120283451-A1 | PROCESS FOR THE PREPARATION OF F-SERIES PROSTAGLANDINS | PTGIS, PTGES, PTGFR | GPR84 2978/4885LMNA 4008/4885FFAR1 241/4885 |
| US-20020002274-A1 | Process for the production of perbenzylated 1-0-glycosides | STT3B, MAN1B1, OSTC | GPR84 4311/4885LMNA 1629/4885FFAR1 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.