Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4178738 | 0.89 | DGKA (0.33) | ADRA2AADRA1ATDP1MAPTBLM | |
| SCHEMBL15401964 | 0.87 | ADRA2A (0.43) | ADRA2AADRA1ATDP1MAPTBLM | |
| SCHEMBL18189732 | 0.86 | CYP2C19 (0.45) | ADRA2AADRA1ATDP1CYP2C19L3MBTL1 | |
| SCHEMBL15401963 | 0.82 | LMNA (0.39) | ADRA2AADRA1ATDP1MAPTBLM | |
| SCHEMBL3182692 | 0.78 | DGKA (0.46) | ADRA2AADRA1ATDP1MAPTBLM | |
| SCHEMBL672318 | 0.78 | — | — | |
| SCHEMBL11342312 | 0.78 | TSHR (0.31) | ADRA2AADRA1ATDP1 | |
| SCHEMBL16550700 | 0.76 | DGKA (0.63) | MAPTDGKA | |
| SCHEMBL2121930 | 0.76 | DGKA (0.44) | DGKA | |
| SCHEMBL11514649 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1637550-B1 | Catalytic processes for the controlled polymerization of free radically (co) polymerizable monomers and functional polymeric systems prepared thereby | UNIV CARNEGIE MELLON (US) | 2017-09-20 | — | — | EP | disclosed |
| US-7825199-B1 | mediated by transition metal complex in redox reaction of atom transfer Atom Transfer Coupling Reaction to/from initiator or dormant polymer and growing active polymer chain ends; transition metal held in close conjunction with a solid support; salt containing a soluble organic counterion; styrene graft | CARNEGIE MELLON UNIVERSITY (US) | 2010-11-02 | — | — | US | disclosed |
| EP-1637550-A2 | Catalytic processes for the controlled polymerization of free radically (co) polymerizable monomers and functional polymeric systems prepared thereby | CARNEGIE-MELLON UNIVERSITY (US) | 2006-03-22 | — | — | EP | disclosed |
| EP-1171496-B1 | CATALYTIC PROCESSES FOR THE CONTROLLED POLYMERIZATION OF FREE RADICALLY (CO)POLYMERIZABLE MONOMERS AND FUNCTIONAL POLYMERIC SYSTEMS PREPARED THEREBY | UNIV CARNEGIE MELLON (US) | 2005-12-07 | — | — | EP | disclosed |
| US-20040171779-A1 | Redox systems; using transition metal complex catalysts; atom transfer radical polymerization | CARNEGIE MELLON UNIVERSITY (A NON-PROFIT PENNSYLVANIA ORGANIZATION) | 2004-09-02 | — | — | US | disclosed |
| EP-1171496-A1 | CATALYTIC PROCESSES FOR THE CONTROLLED POLYMERIZATION OF FREE RADICALLY (CO)POLYMERIZABLE MONOMERS AND FUNCTIONAL POLYMERIC SYSTEMS PREPARED THEREBY | CARNEGIE-MELLON UNIVERSITY (US) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000056795-A1 | CATALYTIC PROCESSES FOR THE CONTROLLED POLYMERIZATION OF FREE RADICALLY (CO)POLYMERIZABLE MONOMERS AND FUNCTIONAL POLYMERIC SYSTEMS PREPARED THEREBY | CARNEGIE MELLON UNIVERSITY (US) | 2000-09-28 | — | — | WO | disclosed |