Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3874912 | 0.85 | ALOX5 (0.44) | KMT2AGAATDP1ALDH1A1HPGD | |
| SCHEMBL4560908 | 0.78 | SLC1A3 (0.44) | KMT2ACYP2C9CYP2C19CYP1A2PKM | |
| SCHEMBL4968147 | 0.78 | ALOX5 (0.44) | KMT2ACYP2C9CYP2C19PKMTDP1 | |
| SCHEMBL7080315 | 0.78 | CYP2C19 (0.42) | KMT2ACYP2C9CYP2C19PKMALDH1A1 | |
| SCHEMBL21881381 | 0.76 | PPARA (0.47) | CYP2C19ALDH1A1KDM4ELMNAPPARG | |
| SCHEMBL6162434 | 0.76 | PPARA (0.47) | CYP2C19ALDH1A1KDM4ELMNAPPARG | |
| SCHEMBL10681281 | 0.76 | — | — | |
| SCHEMBL827441 | 0.76 | — | — | |
| SCHEMBL8228297 | 0.72 | MMP1 (0.45) | KMT2ACYP2C9CYP2C19GAATDP1 | |
| SCHEMBL6044891 | 0.72 | SLC1A3 (0.38) | KMT2ACYP2C19GAAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280113-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2010-11-04 | — | — | US | claimed |
| CN-114727976-A | Use of PPAR-delta agonists in the treatment of renal disease | 雷内奥制药公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-113747891-A | Use of PPAR delta agonists in the treatment of Fatty Acid Oxidation Disorders (FAOD) | 雷内奥制药公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-113710683-A | Use of PPAR-delta agonists in the treatment of mitochondrial myopathy | 雷内奥制药公司 | 2021-11-26 | — | — | CN | disclosed |
| US-20050032646-A1 | Agents for the regulation of gametophytic self-incompatibility and a control method for the breakdown of gametophytic self-incompatibility using the agents | BICBIO CO. LTD. (KR) | 2005-02-10 | — | — | US | disclosed |
| WO-2004036997-A1 | AGENTS FOR THE REGULATION OF GAMETOPHYTIC SELF-INCOMPATIBILITY AND A CONTROL METHOD FOR THE BREAKDOWN OF GAMETOPHYTIC SELF-INCOMPATIBILITY USING THE AGENTS | BICBIO CO., LTD (KR) | 2004-05-06 | — | — | WO | disclosed |
| EP-0395251-A1 | Herbicidal sulfonamides | ICI AUSTRALIA LIMITED (AU) | 1990-10-31 | — | — | EP | disclosed |