Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21881381 | 0.84 | PPARA (0.47) | CYP2C19PPARGPPARAPOLBALDH1A1 | |
| SCHEMBL5934583 | 0.84 | PPARG (0.43) | ALOX5CES2CES1KEAP1CYP2C19 | |
| SCHEMBL6162434 | 0.84 | PPARA (0.47) | CYP2C19PPARGPPARAPOLBALDH1A1 | |
| SCHEMBL24328836 | 0.79 | ALOX5 (0.45) | ALOX5CES2CES1KEAP1CYP2C19 | |
| SCHEMBL11407054 | 0.79 | ALOX5 (0.45) | ALOX5CES2CES1KEAP1CYP2C19 | |
| SCHEMBL12532108 | 0.79 | ALOX5 (0.45) | ALOX5CES2CES1KEAP1CYP2C19 | |
| SCHEMBL7080315 | 0.78 | CYP2C19 (0.42) | ALOX5CES2CES1CYP2C19DAO | |
| SCHEMBL4560908 | 0.78 | SLC1A3 (0.44) | ALOX5CES2CES1CYP2C19DAO | |
| SCHEMBL3740253 | 0.78 | KMT2A (0.51) | ALOX5CYP2C19DAOMMP1MMP2 | |
| SCHEMBL6044891 | 0.76 | SLC1A3 (0.38) | ALOX5CES2CES1KEAP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966196-A2 | PURE AND STABLE TIOTROPIUM BROMIDE | Sicor, Inc. (US) | 2008-09-10 | — | — | EP | claimed |
| US-20070167480-A1 | Pure and stable tiotropium bromide | SICOR INC. (US) | 2007-07-19 | — | — | US | claimed |
| WO-2007075838-A2 | PURE AND STABLE TIOTROPIUM BROMIDE | SICOR INC. (US) | 2007-07-05 | — | — | WO | claimed |
| CN-101360744-A | Pure and stable tiotropium bromide | SICOR INC (US) | 2009-02-04 | — | — | CN | disclosed |
| EP-1966196-A2 | PURE AND STABLE TIOTROPIUM BROMIDE | Sicor, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| EP-1966196-A2 | PURE AND STABLE TIOTROPIUM BROMIDE | Sicor, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007075838-A3 | PURE AND STABLE TIOTROPIUM BROMIDE | SICOR INC (US) | 2007-08-16 | — | — | WO | disclosed |
| US-20070167480-A1 | Pure and stable tiotropium bromide | SICOR INC. (US) | 2007-07-19 | — | — | US | disclosed |
| US-20070167480-A1 | Pure and stable tiotropium bromide | SICOR INC. (US) | 2007-07-19 | — | — | US | disclosed |
| WO-2007075838-A2 | PURE AND STABLE TIOTROPIUM BROMIDE | SICOR INC. (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007075838-A2 | PURE AND STABLE TIOTROPIUM BROMIDE | SICOR INC. (US) | 2007-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167480-A1 | Pure and stable tiotropium bromide | THOP1, GUCY1B2, HSD11B2 | ALOX5 165/4885CES2 4304/4885CES1 3014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.