Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 7/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | RRM1 | P23921 | 1/20 | 0.35 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21758208 | 0.75 | NPC1 (0.47) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL9420910 | 0.75 | NPC1 (0.50) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL2938541 | 0.74 | RAB9A (0.42) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL21046174 | 0.74 | HTR2B (0.49) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL1567105 | 0.74 | RAB9A (0.50) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL21443923 | 0.72 | NPC1 (0.48) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL1567119 | 0.72 | NPC1 (0.50) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL8197052 | 0.72 | HTR7 (0.47) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL30533158 | 0.71 | NPC1 (0.47) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL21436821 | 0.71 | NPC1 (0.47) | NPC1RAB9AHTR2BHTR7PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292163-A1 | Antitumoral Compounds | PHARMA MAR, S.A. (ES) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292163-A1 | Antitumoral Compounds | TP53, XPO1, TOP2B | NPC1 655/4885RAB9A 1796/4885HTR2B 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.