Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | FABP7 | O15540 | 2/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5969982 | 0.76 | FABP5 (0.49) | KMT2ATP53FABP7FABP5 | |
| SCHEMBL6818500 | 0.74 | ACLY (0.36) | POLBFABP7FABP5 | |
| SCHEMBL5481836 | 0.73 | HTR2A (0.47) | KMT2APOLBHTR2AFABP7FABP5 | |
| SCHEMBL29129339 | 0.73 | KMT2A (0.45) | ALDH1A1NPC1RAB9AKMT2APOLB | |
| SCHEMBL3740798 | 0.73 | HTR2A (0.39) | KMT2APOLBMEN1HTR2AFABP7 | |
| SCHEMBL1198306 | 0.72 | HTR2A (0.38) | KMT2APOLBHTR2AFABP7FABP5 | |
| SCHEMBL25373589 | 0.70 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AKMT2AHTT | |
| SCHEMBL16242267 | 0.70 | KMT2A (0.40) | KMT2AHTR2AKDM4EFABP7FABP5 | |
| SCHEMBL3660751 | 0.70 | KMT2A (0.43) | ALDH1A1NPC1RAB9AKMT2AHTT | |
| SCHEMBL17798400 | 0.70 | HTR2A (0.36) | KMT2AHTR2AFABP7FABP5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888543-A4 | AZATIDE PEPTIDOMIMETICS | SCRIPPS RESEARCH INST (US) | 2004-04-07 | — | — | EP | disclosed |
| US-6664372-B1 | Solution phase synthesis on a soluble homopolymer support by reacting tert-butoxycarbonyl-protected aza-amino acids with bis(pentafluorophenyl) carbonate as carbonyl activation element and coupling to support; combinatorial chemistry | THE SCRIPPS RESEARCH INSTITUTE | 2003-12-16 | — | — | US | disclosed |
| EP-0888543-A1 | AZATIDE PEPTIDOMIMETICS | The Scripps Research Institute (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997035199-A9 | AZATIDE PEPTIDOMIMETICS | — | 1997-12-11 | — | — | WO | disclosed |
| WO-1997035199-A1 | AZATIDE PEPTIDOMIMETICS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-09-25 | — | — | WO | disclosed |