Isopropylbenzene

Isopropylbenzene

SCHEMBL374165

CC(C)c1ccccc1.CCCc1ccccc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.49
RAB9A P51151 2/20 0.47
ALDH1A1 P00352 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
EPHX1 P07099 1/20 0.45
NPC1 O15118 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
OPRM1 P35372 2/20 0.44
KCNH2 Q12809 2/20 0.44
CHRM2 P08172 1/20 0.44
HTR1A P08908 1/20 0.44
ADRA2A P08913 1/20 0.44
CHRM1 P11229 1/20 0.44
DRD1 P21728 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
ADRA1A P35348 1/20 0.44
DRD3 P35462 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HTR2A P28223 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropylbenzene SCHEMBL10951391 1.00 SIGMAR1 (0.49) SIGMAR1RAB9AALDH1A1L3MBTL1EPHX1
SCHEMBL27708207 0.96 RAB9A (0.51) SIGMAR1RAB9AALDH1A1L3MBTL1EPHX1
Isopropylbenzene SCHEMBL17318266 0.92 SIGMAR1 (0.44) SIGMAR1RAB9AALDH1A1L3MBTL1EPHX1
Isopropylbenzene SCHEMBL10601589 0.89 MAOA (0.52) SIGMAR1RAB9AALDH1A1L3MBTL1EPHX1
P-Cymene SCHEMBL21544791 0.88 CNR2 (0.50) SIGMAR1RAB9AALDH1A1L3MBTL1EPHX1
Butylbenzyl SCHEMBL8519397 0.88 HTR2A (0.53) SIGMAR1RAB9ANPC1SMN1; SMN2OPRM1
SCHEMBL21056162 0.84 SIGMAR1 (0.53) SIGMAR1ALDH1A1L3MBTL1SLC6A2SLC6A4
SCHEMBL597719 0.84 IDO1 (0.50) SIGMAR1ALDH1A1L3MBTL1KMT2A
Isopropylbenzene SCHEMBL1451617 0.84 TAAR1 (0.48) HTR2A
SCHEMBL40575 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5315049-A Process for the nuclear chlorination of aromatic hydrocarbons BAYER AKTIENGESELLSCHAFT (DE) 1994-05-24 US claimed
CN-108530249-A The method of benzene and isopropylbenzene production n-proplbenzene 中国石油化工股份有限公司 2018-09-14 CN disclosed
CN-108530246-A The method of benzene and production of propylene n-proplbenzene 中国石油化工股份有限公司 2018-09-14 CN disclosed
CN-108530250-A The method of benzene and diisopropylbenzene (DIPB) production n-proplbenzene 中国石油化工股份有限公司 2018-09-14 CN disclosed
CN-108530245-A The method of benzene and isopropyl alcohol production n-proplbenzene 中国石油化工股份有限公司 2018-09-14 CN disclosed
CN-102464565-B Method for producing isopropylbenzene by using benzene and propylene CHINA PETROLEUM & CHEMICAL 2014-08-13 CN disclosed
CN-102464566-B Method for producing isopropylbenzene by using benzene and propylene CHINA PETROLEUM & CHEMICAL 2014-07-23 CN disclosed
CN-102464563-B Method for producing isopropylbenzene CHINA PETROLEUM & CHEMICAL 2013-12-04 CN disclosed
EP-2408880-A2 PROCESS FOR MAKING HIGH OCTANE GASOLINE WITH REDUCED BENZENE CONTENT BY BENZENE ALKYLATION AT HIGH BENZENE CONVERSION ExxonMobil Research and Engineering Company (US) 2012-01-25 EP disclosed
WO-2011076771-A1 PROCESS FOR RECOVERING MONOALKYLBENZENE SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2011-06-30 WO disclosed
WO-2011076952-A1 PROCESS FOR RECOVERING MONOALKYLBENZENE SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2011-06-30 WO disclosed
US-20110118522-A1 OLEFIN FEED PURIFICATION PROCESS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-05-19 US disclosed
WO-2011059878-A1 OLEFIN FEED PURIFICATION PROCESS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-05-19 WO disclosed
CN-1285548-C Process for producing alkylbenzene SINOPEC CORP (CN) 2006-11-22 CN disclosed
CN-1772384-A Prepn of phosphotungstic anion intercalated strontium aluminate hydrotalcite-solid acid alkylation catalyst UNIV SOUTHEAST (CN) 2006-05-17 CN disclosed
CN-1704392-A Process for producing alkylbenzene SINOPEC CORP (CN) 2005-12-07 CN disclosed
CN-1031989-C Process and catalyst compostion of alkylating benzene or substituted benzene or transalkylating alkylated benzene DOW CHEMICAL CO (US) 1996-06-12 CN disclosed
CN-1098028-A Beta-zeolite molecular sieve catalyst and preparation method thereof INST OF TIANJIN PETROCHEMICAL (CN) 1995-02-01 CN disclosed
CN-1052655-A The alkylation of benzene or substituted benzene or the transalkylation method of alkylated benzenes and catalyzer DOW CHEMICAL CO (US) 1991-07-03 CN disclosed
US-3962364-A Alkylation in presence of phosphorus-modified crystalline luminosilicate catalyst MOBIL OIL CORPORATION (US) 1976-06-08 US disclosed