Ethylene Glycol

Ethylene Glycol

SCHEMBL3741933

CCCOC(C(=O)O)C(O)C(=O)O.OCCO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PGD P52209 1/20 0.35
TSHR P16473 2/20 0.33
HCAR2 Q8TDS4 1/20 0.33
CYP2C9 P11712 1/20 0.32
PDE4A P27815 1/20 0.32
CHRM1 P11229 1/20 0.31
AKR1A1 P14550 1/20 0.31
CHRM3 P20309 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
GPR84 Q9NQS5 3/20 0.31
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL3736478 0.93 ACHE (0.33) PGDTSHRHCAR2CYP2C9CHRM1
Di(Hydroxyethyl)Ether SCHEMBL3730840 0.91 TSHR (0.39) PGDTSHRHCAR2TDP1
Propylene Glycol SCHEMBL3738557 0.89 TDP1 (0.36) PGDTSHRHCAR2CYP2C9PDE4A
Ethylene Glycol SCHEMBL3732641 0.89 ATM (0.37) PGDTSHRHCAR2GPR84FFAR1
SCHEMBL234927 0.88 TSHR (0.39) PGDTSHRCYP2C9PDE4A
Ethylene Glycol SCHEMBL3738613 0.84 PGD (0.37) PGDTSHRCYP2C9PDE4A
1,4-Butanediol SCHEMBL3743070 0.84 SMN1; SMN2 (0.37) TSHRHCAR2GPR84FFAR1
SCHEMBL2979038 0.82 ATM (0.41) PGDTSHRHCAR2GPR84FFAR1
Di(Hydroxyethyl)Ether SCHEMBL3742226 0.81 TSHR (0.50) TSHRHCAR2GPR84FFAR1
SCHEMBL3205514 0.81 HCAR2 (0.41) HCAR2CHRM1AKR1A1CHRM3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7825178-B2 Leveling agent for floor polish and aqueous floor polish composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-11-02 US disclosed
US-20070289481-A1 Leveling Agent for Floor Polish and Aqueous Floor Polish Composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-12-20 US disclosed