Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13015783 | 0.86 | HCAR2 (0.36) | HCAR2HDAC1HDAC2CHRM1AKR1A1 | |
| SCHEMBL28140342 | 0.85 | HCAR2 (0.33) | HCAR2HDAC1HDAC2CHRM1AKR1A1 | |
| SCHEMBL1196078 | 0.85 | ATM (0.46) | HCAR2ATMCA2MAPK1GPR84 | |
| SCHEMBL284645 | 0.85 | ATM (0.46) | HCAR2ATMCA2MAPK1GPR84 | |
| SCHEMBL1196777 | 0.85 | ATM (0.46) | HCAR2ATMCA2MAPK1GPR84 | |
| SCHEMBL8081881 | 0.84 | ALDH1A1 (0.36) | HCAR2HDAC1HDAC2CHRM1AKR1A1 | |
| SCHEMBL3960625 | 0.83 | HCAR2 (0.47) | HCAR2GPR84FFAR1 | |
| SCHEMBL5718514 | 0.81 | HCAR2 (0.48) | HCAR2GPR84FFAR1 | |
| SCHEMBL7652872 | 0.81 | HCAR2 (0.48) | HCAR2GPR84FFAR1 | |
| SCHEMBL712622 | 0.81 | HCAR2 (0.48) | HCAR2GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108956799-A | A kind of his Wei of high performance liquid chromatography chiral mobile phases separation hydrochloric acid Dacca and its five kinds of optical isomers | 覃叶枫 | 2018-12-07 | — | — | CN | disclosed |
| CN-108680684-A | A kind of his Wei of high performance liquid chromatography chiral mobile phases separation hydrochloric acid Dacca and its five kinds of optical isomers | 覃叶枫 | 2018-10-19 | — | — | CN | disclosed |
| CN-108645931-A | A kind of his Wei of high performance liquid chromatography chiral mobile phases separation hydrochloric acid Dacca and its five kinds of optical isomers | 覃叶枫 | 2018-10-12 | — | — | CN | disclosed |
| CN-108645930-A | A kind of his Wei of high performance liquid chromatography chiral mobile phases separation hydrochloric acid Dacca and its five kinds of optical isomers | 覃叶枫 | 2018-10-12 | — | — | CN | disclosed |
| CN-108469491-A | A kind of his Wei of high performance liquid chromatography chiral mobile phases separation hydrochloric acid Dacca and its five kinds of optical isomers | 覃叶枫 | 2018-08-31 | — | — | CN | disclosed |
| CN-105504166-B | A kind of sodium alginate-acrylamide composite hydrogel and its preparation method and application | 武汉理工大学 | 2018-06-08 | — | — | CN | disclosed |
| US-20180037840-A1 | THERMOCLEAVABLE FRICTION MODIFIERS AND METHODS THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-02-08 | — | — | US | disclosed |
| US-8642642-B2 | Heterocyclic arylsulphones suitable for treating disorders that respond to modulation of the serotonin 5HT6 receptor | ABBOTT LABORATORIES (US) | 2014-02-04 | — | — | US | disclosed |
| US-8497273-B2 | Heterocyclic compounds suitable for treating disorders that respond to modulation of the serotonin 5HT6 receptor | ABBOTT GMBH & CO. KG (DE) | 2013-07-30 | — | — | US | disclosed |
| US-20100048582-A1 | HETEROCYCLIC COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5HT6 RECEPTOR | ABBOTT GMBH & CO. KG (DE) | 2010-02-25 | — | — | US | disclosed |
| US-20100035997-A1 | KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES | BROADLEY KENNETH N | 2010-02-11 | — | — | US | disclosed |
| US-20100029978-A1 | RAPIDLY CURING CYANOACRYLATES AS ADHESIVES | SWORDS NOELEEN | 2010-02-04 | — | — | US | disclosed |
| US-20090306175-A1 | HETEROCYCLIC ARYLSULPHONES SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5HT6 RECEPTOR | ABBOTT GMBH & CO. KG (DE) | 2009-12-10 | — | — | US | disclosed |
| US-20060241226-A1 | GAP-FILLING CYANOACRYLATE ADHESIVE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-10-26 | — | — | US | disclosed |
| US-6617385-B1 | Alkylene biscyanoacrylate; addition polymer; ester plasticizer | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-09-09 | — | — | US | disclosed |
| EP-0801130-B1 | Surfactant containing microemulsion cleaning composition | SASOL GERMANY GMBH (DE) | 2003-02-05 | — | — | EP | disclosed |
| US-6025503-A | REACTING OPTICALLY ACTIVE(OR RACEMIC) TITANIUM ALKOXIDE COMPLEXES WITH CHIRAL ACTIVATORS(ESPECIALLY DIOLS) YIELDS NEW TITANIUM COMPLEXES WHICH ARE ENANTIO-SELECTIVE IN C-C BOND FORMING REACTIONS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0801130-A2 | Surfactant containing microemulsion cleaning composition | HÜLS AKTIENGESELLSCHAFT (DE) | 1997-10-15 | — | — | EP | disclosed |
| EP-0483606-A2 | Use of polyesters comprising condensed tartaric acid as detergent additive, process for production of the polyesters, and polyesters based upon tartaric acid and tetracarboxylic acids | BASF Aktiengesellschaft (DE) | 1992-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037840-A1 | THERMOCLEAVABLE FRICTION MODIFIERS AND METHODS THEREOF | F12, F5, F3 | HCAR2 4740/4885HDAC1 2330/4885HDAC2 3037/4885 |
| US-20100035997-A1 | KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES | KIT, TEKT1, CUTA | HCAR2 1591/4885HDAC1 4695/4885HDAC2 4813/4885 |
| US-20090306175-A1 | HETEROCYCLIC ARYLSULPHONES SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5HT6 RECEPTOR | HTR6, HTR1A, HTR5A | HCAR2 69/4885HDAC1 1194/4885HDAC2 1396/4885 |
| US-20100029978-A1 | RAPIDLY CURING CYANOACRYLATES AS ADHESIVES | ICAM1, ITGA1, ITGA5 | HCAR2 483/4885HDAC1 3266/4885HDAC2 3603/4885 |
| US-20100048582-A1 | HETEROCYCLIC COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5HT6 RECEPTOR | HTR6, HTR1A, HTR2C | HCAR2 75/4885HDAC1 1225/4885HDAC2 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.