Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | GGT1 | P19440 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29432883 | 0.84 | PTGS2 (0.68) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL338196 | 0.84 | PTGS2 (0.68) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL87637 | 0.83 | PTGS2 (0.57) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| Iodide SCHEMBL30619798 | 0.81 | PTGS2 (0.65) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| Ethylene SCHEMBL28225928 | 0.79 | PTGS2 (0.63) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL8676653 | 0.77 | PTGS2 (0.61) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL19350102 | 0.77 | PTGS2 (0.61) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL10496464 | 0.77 | PTGS2 (0.61) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL236191 | 0.76 | CA12 (0.59) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL30179347 | 0.76 | PTGS2 (0.59) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829044-B2 | Phosphonamides, process for producing the same, and use thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-11-09 | — | — | US | disclosed |
| EP-1496063-B1 | EXTRACTION PROCESS FOR RARE EARTH METAL IONS USING A PHOSPHONAMIDE COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2009-08-19 | — | — | EP | disclosed |
| US-20050107599-A1 | Novel phosphonamides, process for producing the same, and use thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2005-05-19 | — | — | US | disclosed |
| EP-1496063-A1 | NOVEL PHOSPHONAMIDES, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Japan Science and Technology Agency (JP) | 2005-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107599-A1 | Novel phosphonamides, process for producing the same, and use thereof | PHYKPL, CDKL1, MASTL | PTGS2 2828/4885KDM4E 4524/4885HSD17B10 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.