Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3751148 | 0.87 | ALDH1A1 (0.38) | ALDH1A1ALOX15TDP1TRPA1TSHR | |
| SCHEMBL2950776 | 0.74 | KMT2A (0.37) | ALDH1A1TSHRKMT2A | |
| SCHEMBL704584 | 0.73 | ALDH1A1 (0.35) | ALDH1A1TDP1TSHRKMT2A | |
| SCHEMBL21543709 | 0.72 | CA12 (0.50) | ALDH1A1MAOBMAPK1CA12CA1 | |
| SCHEMBL16592686 | 0.72 | GPR3 (0.35) | ALDH1A1ALOX15TDP1TRPA1MAOB | |
| SCHEMBL8179212 | 0.71 | ALDH1A1 (0.60) | ALDH1A1TDP1MAOBTSHRKMT2A | |
| SCHEMBL6744233 | 0.70 | ALDH1A1 (0.34) | ALDH1A1TDP1MAOBTSHR | |
| SCHEMBL28455764 | 0.70 | CYP1A2 (0.41) | ALDH1A1TDP1MAPK1 | |
| SCHEMBL10414995 | 0.69 | ALOX15 (0.43) | ALDH1A1ALOX15TDP1TSHRMAPK1 | |
| SCHEMBL10068086 | 0.69 | MAPT (0.56) | ALDH1A1MAOBCA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834120-B2 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-1645560-B1 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHINETSU CHEMICAL CO (JP) | 2008-05-28 | — | — | EP | disclosed |
| EP-1645560-A1 | Monofunctional monomer having cage oligosiloxane structure and method of making | Shin-Etsu Chemical Co., Ltd. (JP) | 2006-04-12 | — | — | EP | disclosed |
| US-20060074213-A1 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-04-06 | — | — | US | disclosed |