SCHEMBL2950776

SCHEMBL2950776

CCCO[SiH](OCCC)c1cccc([SiH](OCCC)OCCC)c1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.37
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.34
HPGD P15428 2/20 0.33
TSHR P16473 1/20 0.31
LTA4H P09960 1/20 0.31
MEN1 O00255 1/20 0.31
CSNK2A1 P68400 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15736418 0.87 ACHE (0.36) KMT2ALMNA
SCHEMBL8364737 0.87 TSHR (0.44) KMT2AALDH1A1TSHRMEN1
SCHEMBL313696 0.84 LMNA (0.44) KMT2AALDH1A1LMNAHPGDTSHR
SCHEMBL29563626 0.82 KMT2A (0.36) KMT2AALDH1A1LMNAHPGD
SCHEMBL15736499 0.82 ALDH1A1 (0.42) KMT2AALDH1A1LMNATSHRMEN1
SCHEMBL3337785 0.82 LTA4H (0.46) KMT2AALDH1A1LMNATSHRLTA4H
SCHEMBL2959743 0.82 TP53 (0.33)
SCHEMBL704584 0.81 ALDH1A1 (0.35) KMT2AALDH1A1LMNAHPGDTSHR
SCHEMBL19809233 0.79 LMNA (0.40) KMT2AALDH1A1LMNAHPGDTSHR
SCHEMBL6744233 0.79 ALDH1A1 (0.34) ALDH1A1LMNAHPGDTSHRLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100233482-A1 Organic silicon oxide fine particles and preparation method thereof, porous film-forming composition, porous film and formation method thereof, and semiconductor device HAMADA YOSHITAKA 2010-09-16 US disclosed
US-7754330-B2 Organic silicon oxide core-shell particles and preparation method thereof, porous film-forming composition, porous film and formation method thereof, and semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-07-13 US disclosed
US-20090294726-A1 ORGANIC SILICON OXIDE FINE PARTICLES AND PREPARATION METHOD THEREOF, POROUS FILM-FORMING COMPOSITION, POROUS FILM AND FORMATION METHOD THEREOF, AND SEMICONDUCTOR DEVICE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
US-20090294922-A1 ORGANIC SILICON OXIDE FINE PARTICLE AND PREPARATION METHOD THEREOF, POROUS FILM-FORMING COMPOSITION, POROUS FILM AND FORMATION METHOD THEREOF, AND SEMICONDUCTOR DEVICE PANASONIC CORPORATION (JP) 2009-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090294922-A1 ORGANIC SILICON OXIDE FINE PARTICLE AND PREPARATION METHOD THEREOF, POROUS FILM-FORMING COMPOSITION, POROUS FILM AND FORMATION METHOD THEREOF, AND SEMICONDUCTOR DEVICE SPOP, OSTC, SEM1 KMT2A 813/4885ALDH1A1 3005/4885LMNA 1724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.