SCHEMBL3744798

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3741148	1.00	HDAC6 (0.44)	HDAC6ACHEPOLQEPHX2BCHE
	SCHEMBL13041505	0.84	POLQ (0.47)	HDAC6ACHEPOLQESR1THRB
	SCHEMBL3744823	0.83	ALDH1A1 (0.51)	ACHEEPHX2BCHEALDH1A1
	SCHEMBL3731228	0.83	ALDH1A1 (0.51)	ACHEEPHX2BCHEALDH1A1
	SCHEMBL3399062	0.82	POLQ (0.48)	HDAC6ACHEPOLQBCHEESR1
	SCHEMBL3739641	0.81	POLB (0.42)	EPHX2ALDH1A1
	SCHEMBL3748980	0.81	POLB (0.42)	EPHX2ALDH1A1
	SCHEMBL4137692	0.80	EPHX2 (0.52)	HDAC6EPHX2ALDH1A1
	SCHEMBL13041529	0.79	POLQ (0.50)	HDAC6ACHEPOLQBCHEESR1
	SCHEMBL3735946	0.79	KMT2A (0.46)	CDC25BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.