SCHEMBL3748980

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3739641	1.00	POLB (0.42)	POLBTSHRHAO1EPHX2PLK1
	SCHEMBL3731040	0.89	TSHR (0.45)	POLBTSHREPHX2PLK1CES2
	SCHEMBL3735946	0.87	KMT2A (0.46)	POLBTSHRPTPN1KMT2AKDM4E
	SCHEMBL3744823	0.84	ALDH1A1 (0.51)	POLBTSHRHAO1EPHX2CES2
	SCHEMBL3731228	0.84	ALDH1A1 (0.51)	POLBTSHRHAO1EPHX2CES2
	SCHEMBL13041480	0.83	POLB (0.47)	POLBTSHRPTPN1KDM4EALDH1A1
	SCHEMBL10602287	0.82	SOAT2 (0.51)	POLBTSHREPHX2CES1PTPN1
	SCHEMBL3735202	0.82	EPHX2 (0.50)	HAO1EPHX2CES2CES1ASAH1
	SCHEMBL3742708	0.82	EPHX2 (0.50)	HAO1EPHX2CES2CES1ASAH1
	SCHEMBL3744798	0.81	HDAC6 (0.44)	EPHX2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.