Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | CA7 | P43166 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | SCN1A | P35498 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2385707 | 0.98 | NPC1 (0.68) | LTA4HPTGS1PTGS2CA12CA1 | |
| SCHEMBL14204158 | 0.98 | CA12 (0.65) | LTA4HPTGS1PTGS2CA12CA1 | |
| Hydrochloric Acid SCHEMBL14742325 | 0.98 | NPC1 (0.68) | LTA4HPTGS1PTGS2CA12CA1 | |
| SCHEMBL3398830 | 0.95 | LTA4H (0.75) | LTA4HPTGS1PTGS2CA12CA1 | |
| SCHEMBL18763470 | 0.93 | CA12 (0.59) | LTA4HPTGS1PTGS2CA12CA1 | |
| SCHEMBL374569 | 0.92 | HRH3 (0.74) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24398699 | 0.91 | TSHR (0.76) | LTA4HPTGS1PTGS2CA12CA1 | |
| SCHEMBL28126773 | 0.90 | HRH3 (0.68) | NPC1RAB9AALDH1A1MAPK1CYP1A2 | |
| SCHEMBL16314572 | 0.89 | ALDH1A1 (0.66) | NPC1RAB9AALDH1A1MAPK1CYP1A2 | |
| SCHEMBL14724514 | 0.88 | HRH3 (0.71) | NPC1RAB9AALDH1A1MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130030171-A1 | Pyrimidinyl Aryl Urea Derivatives being FGF Inhibitors | NOVARTIS AG (CH) | 2013-01-31 | — | — | US | claimed |
| US-20080312248-A1 | Pyrimidinyl Aryl Urea Derivatives Being Fgf Inhibitors | NOVARTIS AG | 2008-12-18 | — | — | US | claimed |
| EP-1976847-A2 | PYRIMIDINYL ARYL UREA DERIVATIVES BEING FGF INHIBITORS | Novartis AG (CH) | 2008-10-08 | — | — | EP | claimed |
| WO-2007071752-A2 | PYRIMIDINYL ARYL UREA DERIVATIVES BEING FGF INHIBITORS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | claimed |
| EP-4640769-A1 | CONDUCTIVE POLYMER-CONTAINING DISPERSION, SOLID ELECTROLYTE CAPACITOR, AND PRODUCTION METHOD FOR SAME | Resonac Corporation (JP) | 2025-10-29 | — | — | EP | disclosed |
| US-12278061-B1 | Conductive polymer-containing dispersion liquid, solid electrolytic capacitor and method for producing same | RESONAC CORPORATION (JP) | 2025-04-15 | — | — | US | disclosed |
| US-20250118500-A1 | CONDUCTIVE POLYMER-CONTAINING DISPERSION LIQUID, SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PRODUCING SAME | RESONAC CORPORATION (JP) | 2025-04-10 | — | — | US | disclosed |
| EP-4522618-A1 | TETRAHYDROPYRIDO[3,4-D]PYRIMIDINES COMPOUNDS AS HPK1 INHIBITORS | Merck Patent GmbH (DE) | 2025-03-19 | — | — | EP | disclosed |
| US-20250069818-A1 | METHOD FOR PRODUCING POLYMER DISPERSION FOR SOLID ELECTROLYTIC CAPACITOR, AND METHOD FOR PRODUCING SOLID ELECTROLYTIC CAPACITOR | RESONAC CORPORATION (JP) | 2025-02-27 | — | — | US | disclosed |
| EP-4466258-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2024-11-27 | — | — | EP | disclosed |
| EP-4466259-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2024-11-27 | — | — | EP | disclosed |
| US-20240383875-A1 | Benzimidazole Pyridine Derivatives | HOFFMANN-LA ROCHE INC. (US) | 2024-11-21 | — | — | US | disclosed |
| US-6479488-B1 | GOOD IN VITRO AFFINITY FOR THE STRYCHNINE INSENSITIVE GLYCINE BINDING SITE ASSOCIATED WITH THE NMDA RECEPTOR COMPLEX BUT ALSO GOOD IN VIVO ACTIVITY WHEN ADMINISTERED SYSTEMICALLY | GLAXO WELLCOME SPA (IT) | 2002-11-12 | — | — | US | disclosed |
| EP-0922034-B1 | TETRAHYDROQUINOLINE DERIVATIVES AS EAA ANTAGONISTS | GLAXO WELLCOME SPA (IT) | 2002-07-24 | — | — | EP | disclosed |
| EP-0922034-A1 | TETRAHYDROQUINOLINE DERIVATIVES AS EAA ANTAGONISTS | GLAXO WELLCOME S.p.A. (IT) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998007704-A1 | TETRAHYDROQUINOLINE DERIVATIVES AS EAA ANTAGONISTS | GLAXO WELLCOME S.P.A. (IT) | 1998-02-26 | — | — | WO | disclosed |
| EP-0410358-B1 | AROMATIC CARBOXYLIC ACID AMIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-09-29 | — | — | EP | disclosed |
| US-5216153-A | Therapy and prophylaxis for skin, autoimmune and rheumatic diseases | HOFFMANN-LA ROCHE INC. (US) | 1993-06-01 | — | — | US | disclosed |
| US-5128470-A | Aantiinflammatory, antiallergens | HOFFMANN-LA ROCHE INC. (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0410358-A1 | Aromatic carboxylic acid amides, their preparation and their use as medicines | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312248-A1 | Pyrimidinyl Aryl Urea Derivatives Being Fgf Inhibitors | FGFR1, FGF1, FGF2 | LTA4H 3869/4885PTGS1 814/4885PTGS2 895/4885 |
| US-20240383875-A1 | Benzimidazole Pyridine Derivatives | H1-3, H1-2, H1-4 | LTA4H 2346/4885PTGS1 542/4885PTGS2 723/4885 |
| US-20130030171-A1 | Pyrimidinyl Aryl Urea Derivatives being FGF Inhibitors | FGFR1, FGF1, FGF2 | LTA4H 3869/4885PTGS1 814/4885PTGS2 895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.