SCHEMBL374648

SCHEMBL374648

COc1cccc(OC)c1[C]=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
CA7 P43166 3/20 0.50
CA9 Q16790 3/20 0.50
CA12 O43570 2/20 0.50
CA14 Q9ULX7 2/20 0.50
CA4 P22748 1/20 0.50
ALDH1A1 P00352 5/20 0.44
TP53 P04637 2/20 0.44
CYP3A4 P08684 2/20 0.44
HPGD P15428 2/20 0.44
MAPK1 P28482 2/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
HSD17B10 Q99714 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11511313 0.87 CA1 (0.42) CA1CA2CA7CA9CA12
SCHEMBL9113536 0.85 GRIA1 (0.42) CA1CA2CA7CA9CA12
SCHEMBL2960326 0.85 NFE2L2 (0.43) CA1CA2CA7CA9CA12
SCHEMBL10992125 0.83 GABRA1 (0.41) CA1CA2CA7CA9CA12
SCHEMBL2676294 0.76 TDP1 (0.41) ALDH1A1CYP3A4HPGDMAPK1KDM4E
SCHEMBL18245688 0.75 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL2582337 0.75 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL4739158 0.75 RAB9A (0.59) CA1CA2CA7CA9CA12
SCHEMBL2811725 0.75 CYP3A4 (0.30) CYP3A4
SCHEMBL2814633 0.75 IRAK4 (0.44) CA1CA2CA7CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 821 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4347728-A1 UV LED FREE RADICAL CURABLE INKJET INKS AGFA NV (BE) 2024-04-10 EP claimed
US-20240025931-A1 Acylphosphine Oxide Photoinitiators and Applications Thereof AGFA NV (BE) 2024-01-25 US claimed
CN-117440994-A UV LED free radical curable inkjet ink 爱克发有限公司 2024-01-23 CN claimed
US-20230416547-A1 UV Curable Inkjet Inks and Inkjet Printing Methods AGFA NV (BE) 2023-12-28 US claimed
WO-2023232305-A1 INKJET PRINTING METHODS AGFA NV (BE) 2023-12-07 WO claimed
EP-4286483-A1 INKJET PRINTING METHODS AGFA NV (BE) 2023-12-06 EP claimed
EP-4247824-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATORS AND APPLICATIONS THEREOF AGFA NV (BE) 2023-09-27 EP claimed
EP-4247903-A1 UV CURABLE INKJET INKS AND INKJET PRINTING METHODS AGFA NV (BE) 2023-09-27 EP claimed
CN-116438189-A Acyl phosphine oxide photoinitiator and application thereof 爱克发有限公司 2023-07-14 CN claimed
CN-116390929-A UV curable inkjet inks and inkjet printing methods 爱克发有限公司 2023-07-04 CN claimed
US-4171438-A 0-2-Isocephem-4-carboxylic acid derivatives as antibacterial agents BRISTOL-MYERS COMPANY (US) 1979-10-16 US claimed
US-4166905-A ANTIBIOTICS BRISTOL-MYERS COMPANY (US) 1979-09-04 US claimed
US-4166906-A ANTIBIOTICS BRISTOL-MYERS COMPANY (US) 1979-09-04 US claimed
US-4145343-A BACTERICIDES UCB SOCIETE ANONYME (BE) 1979-03-20 US claimed
US-4139628-A ANTIBIOTICS U C B, SOCIETE ANONYME (BE) 1979-02-13 US claimed
US-4118566-A Δ2,3 -1,4-Morpholine-2-carboxylic acid derivatives as antibacterial agents BRISTOL-MYERS COMPANY (US) 1978-10-03 US claimed
US-4113946-A Δ2,3 -1,4-Morpholine-2-carboxylic acid derivatives as antibacterial agents BRISTOL-MYERS COMPANY (US) 1978-09-12 US claimed
US-4112230-A Δ2,3 -1,4 Morpholine-2-carboxylic acid derivatives as antibacterial agents BRISTOL-MYERS COMPANY (US) 1978-09-05 US claimed
US-3984401-A Process for producing lactol-type cephalosporins TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1976-10-05 US claimed
US-3966720-A Process for producing desacetoxy cephalosporanic acid compound NIKKEN CHEMICALS CO., LTD. (JA) 1976-06-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240025931-A1 Acylphosphine Oxide Photoinitiators and Applications Thereof DDO, PAM, SAT1 CA1 1500/4885CA2 1340/4885CA7 1406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.