SCHEMBL374655

SCHEMBL374655

O=C=Nc1ccc(C(c2ccc(N=C=O)cc2)c2ccccc2N=C=O)cc1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.40
TSHR P16473 1/20 0.40
TRPA1 O75762 1/20 0.40
TDP1 Q9NUW8 2/20 0.34
MAPK1 P28482 1/20 0.34
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
MIF P14174 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11468798 0.97 CYP3A4 (0.40) CYP3A4TSHRTRPA1TDP1MAPK1
SCHEMBL4139131 0.84 CYP3A4 (0.46) CYP3A4TSHRTRPA1TDP1MAPK1
SCHEMBL300705 0.84 CYP3A4 (0.44) CYP3A4TRPA1TDP1ALDH1A1GAA
SCHEMBL6841981 0.83 CYP3A4 (0.41) CYP3A4TSHRTRPA1
SCHEMBL365140 0.83 CYP3A4 (0.50) CYP3A4TSHRTRPA1TDP1ALDH1A1
SCHEMBL532582 0.82 CYP3A4 (0.42) CYP3A4TSHRTRPA1TDP1MAPK1
SCHEMBL2909913 0.81 CYP3A4 (0.42) CYP3A4TSHRTRPA1TDP1MAPK1
SCHEMBL295315 0.80 CYP3A4 (0.47) CYP3A4TSHRTRPA1TDP1MAPK1
SCHEMBL8491592 0.79 CYP3A4 (0.44) CYP3A4TSHRTRPA1TDP1MAPK1
SCHEMBL93536 0.79 CYP3A4 (0.54) CYP3A4TSHRTRPA1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9159356-B2 Non-resonant two-photon absorption recording material, non-resonant polymer two-photon absorption optical information recording medium, and recording/reproducing method FUJIFILM CORPORATION (JP) 2015-10-13 US disclosed
US-20140078878-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL, NON-RESONANT POLYMER TWO-PHOTON ABSORPTION OPTICAL INFORMATION RECORDING MEDIUM, AND RECORDING/REPRODUCING METHOD FUJIFILM CORPORATION (JP) 2014-03-20 US disclosed
US-20140064053-A1 NON-RESONANT TWO-PHOTON ABSORPTION MATERIAL, NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL, RECORDING MEDIUM, RECORDING/REPRODUCING METHOD AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND FUJIFILM CORPORATION (JP) 2014-03-06 US disclosed
US-8449794-B2 Non-resonant two-photon absorption recording material and non-resonant two-photon absorption compound FUJIFILM CORPORATION (JP) 2013-05-28 US disclosed
US-20120319059-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND FUJIFILM CORPORATION (JP) 2012-12-20 US disclosed
WO-2012040320-A3 WIND TURBINE WITH MULTI-STAGE BLADES E-NET, LLC (US) 2012-05-10 WO disclosed
WO-2009157975-A3 METHOD FOR TEMPERING AN ALUMINUM ALLOY STANDEX INTERNATIONAL CORPORATION (US) 2012-05-10 WO disclosed
EP-2065890-B1 Optical recording composition and holographic recording medium FUJIFILM CORP (JP) 2012-01-25 EP disclosed
EP-1983516-B1 Optical recording composition and holographic recording medium FUJIFILM CORP (JP) 2011-11-30 EP disclosed
WO-2011102545-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND FUJIFILM CORPORATION (JP) 2011-08-25 WO disclosed
EP-1350814-A1 RADIATION-SENSITIVE COMPOSITION CHANGING IN REFRACTIVE INDEX AND METHOD OF CHANGING REFRACTIVE INDEX JSR Corporation (JP) 2003-10-08 EP disclosed
US-20030187119-A1 Radiation-sensitive composition capable of having refractive index distribution JSR CORPORATION (JP) 2003-10-02 US disclosed
US-20030171468-A1 Radiation-sensitive composition changing in refractive index and utilization thereof JSR CORPORATION (JP) 2003-09-11 US disclosed
US-20030139486-A1 Radiation sensitive refractive index changing composition and refractive index changing method JSR CORPORATION (JP) 2003-07-24 US disclosed
EP-1323742-A2 Radiation sensitive refractive index changing composition and refractive index changing method JSR Corporation (JP) 2003-07-02 EP disclosed
EP-1235104-A1 COMPOSITION HAVING REFRACTIVE INDEX SENSITIVELY CHANGEABLE BY RADIATION AND METHOD FOR FORMING REFRACTIVE INDEX PATTERN JSR Corporation (JP) 2002-08-28 EP disclosed
EP-0880075-B1 Radiation sensitive resin composition JSR CORP (JP) 2001-10-17 EP disclosed
US-5958648-A Radiation sensitive resin composition JSR CORPORATION (JP) 1999-09-28 US disclosed
EP-0880075-A1 Radiation sensitive resin composition JSR Corporation (JP) 1998-11-25 EP disclosed
US-5576398-A POLYCARBODIIMIDES GRAFTED WITH CARBOXYLIC ANHYDRIDE AND EPOXY COMPOUND FOR MOLDING MATERIALS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140078878-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL, NON-RESONANT POLYMER TWO-PHOTON ABSORPTION OPTICAL INFORMATION RECORDING MEDIUM, AND RECORDING/REPRODUCING METHOD PUF60, PARG, FHIT CYP3A4 2561/4885TSHR 4277/4885TRPA1 11/4885
US-20120319059-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND CRY2, KCNJ2, NONO CYP3A4 3211/4885TSHR 2143/4885TRPA1 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.