Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3746947 | 0.96 | CYP2C9 (0.36) | CYP2C9HPGDCYP2C19HTTCASP1 | |
| SCHEMBL14700384 | 0.76 | KLK7 (0.36) | PPARGPPARAALDH1A1 | |
| SCHEMBL6416045 | 0.73 | CYP2C9 (0.41) | CYP2C9HPGDCYP2C19HTTEPHX2 | |
| SCHEMBL2636857 | 0.72 | SMN1; SMN2 (0.35) | LMNA | |
| SCHEMBL14393827 | 0.72 | KMT2A (0.42) | CYP2C9HPGDCYP2C19HTTMETAP2 | |
| SCHEMBL5932136 | 0.71 | ALDH1A1 (0.45) | CYP2C9HPGDCYP2C19HTTEPHX2 | |
| SCHEMBL1295670 | 0.71 | LMNA (0.31) | LMNA | |
| SCHEMBL14700383 | 0.71 | CASP1 (0.37) | CASP1ALDH1A1 | |
| SCHEMBL24111210 | 0.71 | LTA4H (0.46) | — | |
| SCHEMBL8806860 | 0.70 | LMNA (0.36) | CYP2C9CASP1ALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735609-B2 | Bryostatin analogues, synthetic methods and uses | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-05-27 | — | — | US | disclosed |
| US-20100280262-A1 | BRYOSTATIN ANALOGUES, SYNTHETIC METHODS AND USES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280262-A1 | BRYOSTATIN ANALOGUES, SYNTHETIC METHODS AND USES | MCL1, PBK, BID | CYP2C9 4824/4885HPGD 3344/4885CYP2C19 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.