SCHEMBL3747775

SCHEMBL3747775

COCC(O)CCC1CO1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
TSHR P16473 1/20 0.30
PDK1 Q15118 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820347 0.80 ALDH1A1 (0.37) ALDH1A1
SCHEMBL1783303 0.79
SCHEMBL12758702 0.78 ALDH1A1 (0.36) ALDH1A1
SCHEMBL990032 0.77
SCHEMBL28567475 0.77
SCHEMBL991379 0.75 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2
SCHEMBL12391544 0.74 TSHR (0.47) ALDH1A1SMN1; SMN2TSHR
SCHEMBL819773 0.74 ALDH1A1 (0.33) ALDH1A1
SCHEMBL6438635 0.74
SCHEMBL10884022 0.72 THRB (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8889893-B2 Process for the manufacture of 1,2-epoxy-3-chloropropane Solvay (SociétéAnonyme) (BE) 2014-11-18 US disclosed
US-20100331557-A1 PROCESS FOR THE MANUFACTURE OF 1,2-EPOXY-3-CHLOROPROPANE SOLVAY (SOCIETE ANONYME) (BE) 2010-12-30 US disclosed
US-7834202-B2 by reacting allyl chloride (comprises 1,5-hexadiene) and hydrogen peroxide in presence of zeolite catalyst and solvent SOLVAY (SOCIETE ANONYME) (BE) 2010-11-16 US disclosed
US-20080026486-A1 Assay Methods, Materials and Preparations AKUBIO LIMITED (GB) 2008-01-31 US disclosed
US-20080026486-A1 Assay Methods, Materials and Preparations AKUBIO LIMITED (GB) 2008-01-31 US disclosed
US-20060167288-A1 by reacting allyl chloride (comprises 1,5-hexadiene) and hydrogen peroxide in presence of zeolite catalyst and solvent SOLVAY (SOCIETE ANONYME) (BE) 2006-07-27 US disclosed
EP-1575928-A1 PROCESS FOR THE MANUFACTURE OF 1,2-EPOXY-3-CHLOROPROPANE SOLVAY (Société Anonyme) (BE) 2005-09-21 EP disclosed
WO-2004043941-A1 PROCESS FOR THE MANUFACTURE OF 1,2-EPOXY-3-CHLOROPROPANE Solvay (Société Anonyme) (BE) 2004-05-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080026486-A1 Assay Methods, Materials and Preparations SCLY, ZYX, TST ALDH1A1 2598/4885SMN1; SMN2 1261/4885TSHR 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.