SCHEMBL3747895

SCHEMBL3747895

O=C1OC2(C3=CC=C(CCl)CC13)c1cc(Cl)c(O)cc1Oc1cc(O)c(Cl)cc12

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2784206 0.83 FTO (0.34) FTO
SCHEMBL332302 0.81 FTO (0.36) FTO
SCHEMBL3977228 0.73 FTO (0.32) FTO
SCHEMBL147188 0.73 FTO (0.33) FTO
SCHEMBL4575132 0.71 FTO (0.34) FTO
SCHEMBL8336070 0.70 FTO (0.32) FTO
SCHEMBL4344779 0.66 FTO (0.38) FTO
SCHEMBL4278233 0.65 DHFR (0.39) FTO
SCHEMBL1469054 0.65 GSTP1 (0.49) FTO
SCHEMBL1470877 0.65 GSTP1 (0.60) FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838503-B2 Methods for extending the replicative lifespan of cells CHILDREN'S MEDICAL CENTER CORPORATION (US) 2010-11-23 US disclosed
US-20070160586-A1 Methods for extending the replicative lifespan of cells CHILDREN'S MEDICAL CENTER CORPORATION (US) 2007-07-12 US disclosed