Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 3/20 | 0.39 |
| ▸ | TYMS | P04818 | 3/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336896 | 0.83 | FTO (0.59) | DHFRTYMSFTOHPGDMEN1 | |
| SCHEMBL12488503 | 0.82 | HPGD (0.51) | DHFRTYMSFTOHPGDMEN1 | |
| SCHEMBL15349331 | 0.82 | GSTP1 (0.48) | FTOHPGDMEN1KMT2ARECQL | |
| SCHEMBL1468956 | 0.81 | ALDH1A1 (0.40) | DHFRTYMSFTOHPGDMEN1 | |
| SCHEMBL19211134 | 0.80 | DHFR (0.47) | DHFRTYMSFTOHPGDMEN1 | |
| SCHEMBL5316637 | 0.80 | FTO (0.41) | DHFRTYMSFTOHPGDMEN1 | |
| SCHEMBL6338860 | 0.79 | LCK (0.39) | DHFRTYMSFTOHPGDMEN1 | |
| SCHEMBL1689593 | 0.79 | ALDH1A1 (0.44) | DHFRTYMSFTOHPGDMEN1 | |
| Dichlorofluorescein SCHEMBL29364373 | 0.77 | MAPT (0.64) | DHFRTYMSFTOHPGDMEN1 | |
| Dichlorofluorescein SCHEMBL30606648 | 0.77 | MAPT (0.64) | DHFRTYMSFTOHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018119432-A1 | ANGIOGENIN-BORONIC ACID CONJUGATES WITH SELECTIVE NEUROPROTECTION ACTIVITY | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2018-06-28 | — | — | WO | disclosed |
| US-8193160-B2 | System for inhibiting pathogenicity in the rice-blast fungus Magnaporthe grisea | TEMASEK LIFE SCIENCES LABORATORY (SG) | 2012-06-05 | — | — | US | disclosed |
| US-20090099088-A1 | System for Inhibiting Pathogenicity in the Rice-Blast Fungus Magnaporthe Grisea | TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) | 2009-04-16 | — | — | US | disclosed |