Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31384301 | 0.85 | KDM4E (0.61) | PTPN1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL31384359 | 0.85 | PKM (0.59) | ALDH1A1KDM4ESMN1; SMN2GAANPC1 | |
| SCHEMBL114885 | 0.84 | CA1 (0.67) | PTPN1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5202186 | 0.83 | NPC1 (0.68) | PTPN1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL166289 | 0.83 | POLB (0.67) | PTPN1ALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL31384371 | 0.83 | HPGD (0.58) | PTPN1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL4831697 | 0.83 | SMN1; SMN2 (0.64) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL31384335 | 0.83 | HPGD (0.58) | PTPN1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL12831210 | 0.82 | PTPN1 (0.69) | PTPN1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2330752 | 0.82 | PTPN1 (0.93) | PTPN1ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504731-A | Naringenin derivative containing 1,3, 4-oxadiazole acylhydrazone structure and preparation method thereof | 广东省科学院测试分析研究所(中国广州分析测试中心) | 2025-02-25 | — | — | CN | disclosed |
| US-7838543-B2 | Melanin Concentrating Hormone Receptor 1; Obesity; 4'-Fluoro-biphenyl-4-carboxylic acid {2-[(2-dimethylamino-ethyl)-methyl-amino]-benzothiazol-6-yl}amide; 4-Cyclohexyl-N-{2-[(2-dimethylamino-ethyl)-methyl-amino]-benzooxazol-5-yl}-benzamide; 2-aminobenzoxazoles or 2-aminobenzothiazoles | ELI LILLY AND COMPANY (US) | 2010-11-23 | — | — | US | disclosed |
| US-20090170913-A1 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY | 2009-07-02 | — | — | US | disclosed |
| EP-1828177-B1 | NOVEL MCH RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-08-13 | — | — | EP | disclosed |
| US-20080096931-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-24 | — | — | US | disclosed |
| US-20080096931-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-24 | — | — | US | disclosed |
| US-20080096931-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-24 | — | — | US | disclosed |
| US-7351724-B2 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-01 | — | — | US | disclosed |
| US-7351724-B2 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-01 | — | — | US | disclosed |
| US-7351724-B2 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-01 | — | — | US | disclosed |
| EP-1828177-A2 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2007-09-05 | — | — | EP | disclosed |
| EP-1812427-A1 | OXADIAZOLE KETONE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | The Scripps Research Institute (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006066173-A2 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2006-06-22 | — | — | WO | disclosed |
| US-20060100212-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-05-11 | — | — | US | disclosed |
| WO-2006044617-A1 | OXADIAZOLE KETONE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100212-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | FAAH, FAAH2, HCRTR2 | PTPN1 4444/4885ALDH1A1 408/4885KDM4E 353/4885 |
| US-20090170913-A1 | NOVEL MCH RECEPTOR ANTAGONISTS | MCHR1, MCHR2, MC1R | PTPN1 812/4885ALDH1A1 1529/4885KDM4E 2042/4885 |
| US-20080096931-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | FAAH, FAAH2, HCRTR2 | PTPN1 4444/4885ALDH1A1 408/4885KDM4E 353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.