Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 2/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963234 | 0.83 | NR3C1 (0.42) | NR3C1FFAR1XDHESRRA | |
| SCHEMBL3751204 | 0.81 | AR (0.49) | NR3C1FFAR1ICMTTRPV4 | |
| SCHEMBL31432137 | 0.78 | TRPV4 (0.38) | ICMTTRPV4 | |
| SCHEMBL27642753 | 0.78 | CTSS (0.44) | TRPV4ESRRA | |
| SCHEMBL3495657 | 0.78 | CTSS (0.44) | TRPV4ESRRA | |
| SCHEMBL12619038 | 0.77 | NR3C1 (0.45) | NR3C1FFAR1 | |
| SCHEMBL29408152 | 0.77 | NR3C1 (0.39) | NR3C1FFAR1ESRRA | |
| SCHEMBL22658071 | 0.77 | NR3C1 (0.39) | NR3C1FFAR1ESRRA | |
| SCHEMBL944720 | 0.77 | TRPV4 (0.53) | FFAR1TRPV4 | |
| SCHEMBL1303516 | 0.77 | NR3C1 (0.39) | NR3C1FFAR1TRPV4ESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103333134-A | 2-(3-cyano-4-alkoxy) phenyl-4-substituted thiazole-5-formic acid compound, composition as well as preparation methods and applications thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-10-02 | — | — | CN | disclosed |