Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3757552 | 1.00 | ALDH1A1 (0.68) | ALDH1A1POLBSIRT2SIRT1ADAMTS4 | |
| SCHEMBL3759433 | 0.88 | ALDH1A1 (0.73) | ALDH1A1POLBSIRT2SIRT1LOXL2 | |
| SCHEMBL28426090 | 0.88 | ALDH1A1 (0.73) | ALDH1A1POLBSIRT2SIRT1LOXL2 | |
| Hydrochloric Acid SCHEMBL8123779 | 0.86 | ALDH1A1 (0.71) | ALDH1A1POLBLOXL2AOC3MEN1 | |
| SCHEMBL20021998 | 0.85 | ALDH1A1 (0.69) | ALDH1A1POLBADAMTS4MEN1KMT2A | |
| SCHEMBL14619788 | 0.85 | ALDH1A1 (0.69) | ALDH1A1POLBGFERTSHRCNR1 | |
| SCHEMBL28423968 | 0.85 | ALDH1A1 (0.69) | ALDH1A1POLBGFERTSHRCNR1 | |
| SCHEMBL120374 | 0.84 | POLB (0.68) | ALDH1A1POLBSIRT2SIRT1ADAMTS4 | |
| SCHEMBL1287373 | 0.83 | ALDH1A1 (0.68) | ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1287280 | 0.83 | ALDH1A1 (0.68) | ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222160-B1 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | PHARMAXIS LTD (AU) | 2015-03-18 | — | — | EP | disclosed |
| US-8426587-B2 | Haloallylamine inhibitors of SSAO/VAP-1 and uses therefor | PHARMAXIS LTD. (AU) | 2013-04-23 | — | — | US | disclosed |
| US-20100298330-A1 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | PHARMAXIS LTD. (AU) | 2010-11-25 | — | — | US | disclosed |
| US-4585483-A | Recording materials | FUJI PHOTO FILM CO., LTD. (JP) | 1986-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298330-A1 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | VAPA, SLC6A11, VAPB | ALDH1A1 118/4885POLB 1598/4885SIRT2 2871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.