Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.62 |
| ▸ | HTR1A | P08908 | 9/20 | 0.62 |
| ▸ | HTR7 | P34969 | 9/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 9/20 | 0.57 |
| ▸ | HTR2C | P28335 | 3/20 | 0.57 |
| ▸ | HRH1 | P35367 | 3/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30093447 | 1.00 | DRD2 (0.62) | DRD2HTR1AHTR7SLC6A4NPC1 | |
| SCHEMBL28919882 | 1.00 | DRD2 (0.62) | DRD2HTR1AHTR7SLC6A4NPC1 | |
| SCHEMBL1668218 | 1.00 | DRD2 (0.62) | DRD2HTR1AHTR7SLC6A4NPC1 | |
| SCHEMBL28919881 | 0.99 | DRD2 (0.63) | DRD2HTR1AHTR7SLC6A4NPC1 | |
| Bromide SCHEMBL28956727 | 0.97 | DRD2 (0.62) | DRD2HTR1AHTR7SLC6A4NPC1 | |
| SCHEMBL19043117 | 0.94 | DRD2 (0.61) | DRD2HTR1AHTR7SLC6A4NPC1 | |
| SCHEMBL1667888 | 0.92 | FAAH (0.58) | DRD2HTR1AHTR7SLC6A4NPC1 | |
| SCHEMBL1667887 | 0.92 | FAAH (0.58) | DRD2HTR1AHTR7SLC6A4NPC1 | |
| SCHEMBL12548965 | 0.88 | NPC1 (0.63) | DRD2HTR1AHTR7SLC6A4NPC1 | |
| SCHEMBL28172146 | 0.86 | DRD2 (0.62) | DRD2HTR1AHTR7SLC6A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838522-B2 | Benzothiazole formulations and use thereof | ARES TRADING S.A. (CH) | 2010-11-23 | — | — | US | disclosed |
| US-20080051397-A1 | Benzothiazole Formulations and Use Thereof | ARES TRADING S.A. (CH) | 2008-02-28 | — | — | US | disclosed |
| CN-101102796-A | Benzothiazole formulations and uses thereof | ARES TRADING SA (CH) | 2008-01-09 | — | — | CN | disclosed |
| EP-1812072-A2 | BENZOTHIAZOLE FORMULATIONS AND USE THEREOF | Ares Trading S.A. (CH) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006053882-A3 | BENZOTHIAZOLE FORMULATIONS AND USE THEREOF | ARES TRADING SA (CH) | 2006-09-08 | — | — | WO | disclosed |
| WO-2006053882-A2 | BENZOTHIAZOLE FORMULATIONS AND USE THEREOF | ARES TRADING S.A. (CH) | 2006-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051397-A1 | Benzothiazole Formulations and Use Thereof | MGLL, MBOAT4, MBOAT1 | DRD2 1796/4885HTR1A 1209/4885HTR7 705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.