SCHEMBL375288

SCHEMBL375288

CO[Si](CC(S)CS)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
HTT P42858 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC22A6 Q4U2R8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28122465 0.84
SCHEMBL17076287 0.79
SCHEMBL3688378 0.76
SCHEMBL375970 0.75 NR1I2 (0.31) NR1I2ALDH1A1LMNACYP1A2HTT
SCHEMBL29211125 0.75
SCHEMBL375796 0.74
SCHEMBL2107265 0.72
SCHEMBL7155164 0.72 LMNA (0.38) LMNA
SCHEMBL375250 0.72
SCHEMBL28574189 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109020751-B Preparation method of functional soil biological remediation fertilizer based on nutrient organic carbon skeleton 天津大学 2021-04-23 CN claimed
US-12139635-B2 Coatings for waterproofing electronic components HENKEL AG & CO. KGAA (DE) 2024-11-12 US disclosed
US-20220002559-A1 COATINGS FOR WATERPROOFING ELECTRONIC COMPONENTS HENKEL AG & CO. KGAA (DE) 2022-01-06 US disclosed
CN-109020751-B Preparation method of functional soil biological remediation fertilizer based on nutrient organic carbon skeleton 天津大学 2021-04-23 CN disclosed
CN-110752687-A Resin composition for fixing, rotor, automobile, and method for producing rotor 住友电木株式会社 2020-02-04 CN disclosed
US-20140005432-A1 PROCESS FOR PREPARING ORGANOSILANES EVONIK DEGUSSA GMBH (DE) 2014-01-02 US disclosed
EP-2408785-A1 PROCESS FOR PREPARING ORGANOSILANES Evonik Degussa GmbH (DE) 2012-01-25 EP disclosed
WO-2010105434-A1 PROCESS FOR PREPARING ORGANOSILANES EVONIK DEGUSSA GMBH (DE) 2010-09-23 WO disclosed
US-7501534-B2 Process for the preparation of organosilanes DEGUSSA AG (DE) 2009-03-10 US disclosed
EP-1700861-B1 Process for preparing organosilanes DEGUSSA (DE) 2007-08-15 EP disclosed
US-7019160-B2 Process for the preparation of (mercaptoorganyl)alkoxysilanes DEGUSSA AG (DE) 2006-03-28 US disclosed
EP-1538152-B1 Process for the preparation of (mercaptoorganyl)-alkoxysilanen DEGUSSA (DE) 2006-03-22 EP disclosed
US-6995280-B2 Process for preparing (mercaptoorganyl)alkoxysilanes DEGUSSA AG (DE) 2006-02-07 US disclosed
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 US disclosed
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 US disclosed
EP-1538152-A1 Process for the preparation of (mercaptoorganyl)-alkoxysilanen Degussa AG (DE) 2005-06-08 EP disclosed
EP-1529782-A1 Process for preparing mercaptoorganyl alkoxy silanes Degussa AG (DE) 2005-05-11 EP disclosed
US-5332801-A For blends MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1994-07-26 US disclosed
US-5120800-A Boriding with borane compound having at least one boron-hydrogen bond and oxidizing MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1992-06-09 US disclosed
EP-0451819-A2 Process for preparing modified-polyphenylene ether MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes ADH1C, ADH1A, MPST NR1I2 4191/4885ALDH1A1 670/4885LMNA 3513/4885
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes MPST, ADH1A, ADH1C NR1I2 4268/4885ALDH1A1 208/4885LMNA 4012/4885
US-20140005432-A1 PROCESS FOR PREPARING ORGANOSILANES MPST, STS, CYP2S1 NR1I2 2233/4885ALDH1A1 1390/4885LMNA 4164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.