SCHEMBL3752942

SCHEMBL3752942

Oc1cccc(O)c1C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
POLB P06746 1/20 0.52
GAA P10253 1/20 0.52
GFER P55789 1/20 0.52
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
ALOX12 P18054 1/20 0.43
HTT P42858 1/20 0.43
ATM Q13315 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HSD17B10 Q99714 1/20 0.43
EPHX2 P34913 5/20 0.43
LMNA P02545 3/20 0.42
FAAH O00519 2/20 0.41
NPC1 O15118 1/20 0.41
CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL548653 0.88 MEN1 (0.59) MEN1KMT2APOLBGAAGFER
SCHEMBL549642 0.88 MEN1 (0.46) MEN1KMT2APOLBGAAGFER
SCHEMBL3752409 0.87 MEN1 (0.44) MEN1KMT2APOLBGAAGFER
SCHEMBL27705429 0.86 MEN1 (0.44) MEN1KMT2APOLBGAAGFER
SCHEMBL27419644 0.86 MEN1 (0.44) MEN1KMT2APOLBGAAGFER
SCHEMBL4677956 0.83 MEN1 (0.53) MEN1KMT2APOLBGAAGFER
SCHEMBL3752189 0.82 POLB (0.38) MEN1KMT2APOLBGAAGFER
SCHEMBL12760778 0.82 ERN1 (0.47) MEN1KMT2APOLBGAAGFER
SCHEMBL18040209 0.82 KDM4E (0.49) MEN1KMT2APOLBGAAGFER
SCHEMBL31490948 0.80 ALDH1A1 (0.48) MEN1KMT2APOLBGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104004187-B Polyimide having side chain group and method for producing same 欣兴电子股份有限公司 2016-06-08 CN disclosed
CN-104016950-A Dianhydride monomer with side chain group, polyimide and preparation method thereof UNIMICRON TECHNOLOGY CORP 2014-09-03 CN disclosed
CN-104003889-A Diamine monomer with side chain group, polyimide and preparation method thereof UNIMICRON TECHNOLOGY CORP 2014-08-27 CN disclosed
CN-104004187-A Polyimide having side chain group and method for producing same UNIMICRON TECHNOLOGY CORP 2014-08-27 CN disclosed
US-8084650-B2 Adamantane derivative, resin composition containing same, and optoelectronic member and sealing agent for electronic circuit using those IDEMITSU KOSAN CO., LTD. (JP) 2011-12-27 US disclosed
US-7863347-B2 Resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-20100298491-A1 ADAMANTANE DERIVATIVE, RESIN COMPOSITION CONTAINING SAME, AND OPTOELECTRONIC MEMBER AND SEALING AGENT FOR ELECTRONIC CIRCUIT USING THOSE IDEMITSU KOSAN CO., LTD. (JP) 2010-11-25 US disclosed
CN-101547885-A Adamantane derivative, process for producing the same, and resin composition containing adamantane derivative IDEMITSU KOSAN CO (JP) 2009-09-30 CN disclosed
EP-1985616-A1 ADAMANTANE DERIVATIVE, RESIN COMPOSITION CONTAINING SAME, AND OPTOELECTRONIC MEMBER AND SEALING AGENT FOR ELECTRONIC CIRCUIT USING THOSE Idemitsu Kosan Co., Ltd. (JP) 2008-10-29 EP disclosed
CN-1117966-A Biphenyl derivatives EISAI CO LTD (JP) 1996-03-06 CN disclosed
US-4131656-A Intermediates for 5-(tertiary alkyl) resorcinol preparation ELI LILLY AND COMPANY (US) 1978-12-26 US disclosed
US-4087410-A 5-(Tertiary alkyl) resorcinol preparation and intermediates therefor ELI LILLY AND COMPANY (US) 1978-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298491-A1 ADAMANTANE DERIVATIVE, RESIN COMPOSITION CONTAINING SAME, AND OPTOELECTRONIC MEMBER AND SEALING AGENT FOR ELECTRONIC CIRCUIT USING THOSE AOC1, ASIC1, ICAM1 MEN1 2523/4885KMT2A 4159/4885POLB 2866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.