SCHEMBL3752189

SCHEMBL3752189

Oc1cccc(O)c1C12CC3CC(c4c(O)cccc4O)(C1)CC(c1c(O)cccc1O)(C3)C2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
GAA P10253 1/20 0.38
GFER P55789 1/20 0.38
ALDH1A1 P00352 4/20 0.36
HPGD P15428 4/20 0.36
HSD17B10 Q99714 4/20 0.36
CA2 P00918 3/20 0.36
ALOX15 P16050 3/20 0.36
RECQL P46063 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
EGFR P00533 2/20 0.36
LMNA P02545 2/20 0.36
FYN P06241 2/20 0.36
MMP9 P14780 2/20 0.36
CA1 P00915 2/20 0.36
ADAMTS4 O75173 1/20 0.36
MMP2 P08253 1/20 0.36
MMP8 P22894 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3752409 0.87 MEN1 (0.44) POLBMEN1KMT2AGAAGFER
SCHEMBL27847914 0.85 GRIN1 (0.40) LMNANPC1NFKB1MTORPMP22
SCHEMBL3757087 0.83 ALOX15 (0.45) POLBMEN1KMT2AALDH1A1HPGD
SCHEMBL3757018 0.83 MEN1 (0.40) POLBMEN1KMT2AGAAGFER
SCHEMBL3752942 0.82 MEN1 (0.52) POLBMEN1KMT2AGAAGFER
SCHEMBL3767278 0.80 MEN1 (0.37) POLBMEN1KMT2AGAAGFER
SCHEMBL3763998 0.79 ALDH1A1 (0.41) POLBMEN1KMT2AGAAGFER
SCHEMBL12804771 0.73 KDM4E (0.39) POLBMEN1KMT2AGAAGFER
SCHEMBL3757968 0.72 KMT2A (0.40) POLBMEN1KMT2AGAAGFER
SCHEMBL237723 0.71 GRIN2D (0.43) POLBMEN1KMT2AGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8084650-B2 Adamantane derivative, resin composition containing same, and optoelectronic member and sealing agent for electronic circuit using those IDEMITSU KOSAN CO., LTD. (JP) 2011-12-27 US disclosed
US-20100298491-A1 ADAMANTANE DERIVATIVE, RESIN COMPOSITION CONTAINING SAME, AND OPTOELECTRONIC MEMBER AND SEALING AGENT FOR ELECTRONIC CIRCUIT USING THOSE IDEMITSU KOSAN CO., LTD. (JP) 2010-11-25 US disclosed
EP-1985616-A1 ADAMANTANE DERIVATIVE, RESIN COMPOSITION CONTAINING SAME, AND OPTOELECTRONIC MEMBER AND SEALING AGENT FOR ELECTRONIC CIRCUIT USING THOSE Idemitsu Kosan Co., Ltd. (JP) 2008-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298491-A1 ADAMANTANE DERIVATIVE, RESIN COMPOSITION CONTAINING SAME, AND OPTOELECTRONIC MEMBER AND SEALING AGENT FOR ELECTRONIC CIRCUIT USING THOSE AOC1, ASIC1, ICAM1 POLB 2866/4885MEN1 2523/4885KMT2A 4159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.