Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.72 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | AR | P10275 | 3/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.61 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TNF | P01375 | 1/20 | 0.57 |
| ▸ | IL6 | P05231 | 1/20 | 0.57 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.57 |
| ▸ | GLUL | P15104 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prednisolone Valerate Acetate SCHEMBL14339603 | 1.00 | PGR (0.72) | PGRHIF1ANR3C1LMNACYP3A4 | |
| Prednisolone Valerate Acetate SCHEMBL375319 | 1.00 | PGR (0.72) | PGRHIF1ANR3C1LMNACYP3A4 | |
| SCHEMBL391631 | 0.94 | PGR (0.74) | PGRHIF1ANR3C1LMNACYP3A4 | |
| SCHEMBL5602245 | 0.93 | PGR (0.80) | PGRHIF1ANR3C1LMNACYP3A4 | |
| SCHEMBL5602237 | 0.93 | PGR (0.80) | PGRHIF1ANR3C1LMNACYP3A4 | |
| SCHEMBL730945 | 0.92 | HIF1A (0.79) | PGRHIF1ANR3C1LMNACYP3A4 | |
| SCHEMBL11436847 | 0.92 | PGR (0.76) | PGRHIF1ANR3C1LMNACYP3A4 | |
| SCHEMBL10940343 | 0.92 | PGR (0.69) | PGRHIF1ANR3C1LMNACYP3A4 | |
| SCHEMBL10940339 | 0.92 | PGR (0.69) | PGRHIF1ANR3C1LMNACYP3A4 | |
| SCHEMBL2299113 | 0.91 | PGR (0.78) | PGRHIF1ANR3C1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 642 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4744657-A1 | THERAPEUTIC AGENT FOR HUMAN GRAFT VERSUS HOST DISEASE AND COMBINATION THEREOF | National University Corporation Okayama University (JP) | 2026-05-20 | — | — | EP | claimed |
| US-20250332120-A1 | COMPOSITION FOR EXTERNAL PREPARATION | KAO CORPORATION (JP) | 2025-10-30 | — | — | US | claimed |
| US-20250170069-A1 | NANOPREPARATION FOR JOINT ANALGESIA, AND PREPARATION METHOD AND USE THEREOF | XIANGYA HOSPITAL CENTRAL SOUTH UNIV (CN) | 2025-05-29 | — | — | US | claimed |
| CN-119894520-A | External skin preparation composition | 志瑞亚新药工业株式会社 | 2025-04-25 | — | — | CN | claimed |
| EP-4470532-A1 | NANO PREPARATION FOR JOINT ANALGESIA, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Xiangya Hospital, Central South University (CN) | 2024-12-04 | — | — | EP | claimed |
| WO-2024058193-A1 | COMPOSITION FOR EXTERNAL PREPARATION FOR SKIN | ゼリア新薬工業株式会社 | 2024-03-21 | — | — | WO | claimed |
| CN-114126574-B | External preparation for skin | 花王株式会社 | 2023-11-21 | — | — | CN | claimed |
| WO-2023160631-A1 | NANO PREPARATION FOR JOINT ANALGESIA, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中南大学湘雅医院 | 2023-08-31 | — | — | WO | claimed |
| US-11376262-B2 | Method of treating an inflammatory or infectious disease | ACTIVUS PHARMA CO., LTD. (JP) | 2022-07-05 | — | — | US | claimed |
| CN-107613985-B | Aqueous suspensions of nanoparticles containing glucocorticoids | 株式会社活效制药 | 2021-05-25 | — | — | CN | claimed |
| US-20090012051-A1 | EXTERNAL PREPARATION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-01-08 | — | — | US | claimed |
| US-20070287689-A1 | Therapeutic And/Or Preventive Agents For Chronic Skin Diseases | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-12-13 | — | — | US | claimed |
| CN-101053552-A | O/W type emulsification preparation containing prednisolone valerate acetate | KOWA CO (JP) | 2007-10-17 | — | — | CN | claimed |
| EP-1810692-A1 | REMEDIES/PREVENTIVES FOR CHRONIC SKIN DISEASE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-07-25 | — | — | EP | claimed |
| US-20070128273-A1 | Composition containing medicine extremely slightly soluble in water and method for preparation thereof | KOWA CO., LTD. (JP) | 2007-06-07 | — | — | US | claimed |
| EP-1097712-B1 | STEROID-CONTAINING CATAPLASMS AND PROCESS FOR PRODUCING THE SAME | HISAMITSU PHARMACEUTICAL CO (JP) | 2003-10-01 | — | — | EP | claimed |
| US-6432431-B1 | GEL PATCHES CONTAINING CROTAMITON, CURING AGENTS, NONIONIC SURFACTANTS AND STEROLS ON NON-WOVEN FABRIC SUPPORTS HAVING AIR PERMEABILITY AND STORGE STABILITY; USED FOR ECZEMA, DERMATITIS AND ATOPIC DISEASES | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2002-08-13 | — | — | US | claimed |
| EP-1097712-A1 | STEROID-CONTAINING CATAPLASMS AND PROCESS FOR PRODUCING THE SAME | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2001-05-09 | — | — | EP | claimed |
| WO-1997027862-A1 | SUPPLEMENTATION OF GLUCOCORTICOIDS | BELLARA MEDICAL PRODUCTS LIMITED (AU) | 1997-08-07 | — | — | WO | claimed |
| US-5236906-A | Adrenocortical hormone and hyaluronic acid; skin diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012051-A1 | EXTERNAL PREPARATION | CYP4A11, CYP46A1, CYP11B2 | PGR 2297/4885HIF1A 1229/4885NR3C1 556/4885 |
| US-20070287689-A1 | Therapeutic And/Or Preventive Agents For Chronic Skin Diseases | PDE4A, PDE3B, PDE2A | PGR 1575/4885HIF1A 2269/4885NR3C1 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.