Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.80 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.80 |
| ▸ | LMNA | P02545 | 4/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.80 |
| ▸ | USP2 | O75604 | 1/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.80 |
| ▸ | AR | P10275 | 4/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.73 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.63 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.59 |
| ▸ | TNF | P01375 | 1/20 | 0.59 |
| ▸ | IL6 | P05231 | 1/20 | 0.59 |
| ▸ | GLUL | P15104 | 1/20 | 0.59 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5602237 | 1.00 | PGR (0.80) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL11422082 | 0.95 | NR3C1 (0.88) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL9487612 | 0.93 | PGR (0.78) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL2299113 | 0.93 | PGR (0.78) | PGRNR3C1HIF1ALMNACYP3A4 | |
| Prednisolone Valerate Acetate SCHEMBL375318 | 0.93 | PGR (0.72) | PGRNR3C1HIF1ALMNACYP3A4 | |
| Prednisolone Valerate Acetate SCHEMBL14339603 | 0.93 | PGR (0.72) | PGRNR3C1HIF1ALMNACYP3A4 | |
| Prednisolone Valerate Acetate SCHEMBL375319 | 0.93 | PGR (0.72) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL10940461 | 0.93 | PGR (0.72) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL10940470 | 0.93 | PGR (0.72) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL11016450 | 0.92 | PGR (0.80) | PGRNR3C1HIF1ALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610511-B2 | COMPOSITION FOR DERMATOLOGIC PREPARATION | SHISEIDO CO LTD (JP) | 2007-08-01 | — | — | EP | claimed |
| EP-0610511-A1 | COMPOSITION FOR DERMATOLOGIC PREPARATION | SHISEIDO COMPANY LIMITED (JP) | 1994-08-17 | — | — | EP | claimed |
| EP-0610511-B2 | COMPOSITION FOR DERMATOLOGIC PREPARATION | SHISEIDO CO LTD (JP) | 2007-08-01 | — | — | EP | disclosed |
| EP-0610511-B1 | COMPOSITION FOR DERMATOLOGIC PREPARATION | SHISEIDO CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-5962000-A | VITAMIN A AND AN ANTIINFLAMMATORY DRUG SELECTED FROM THE GROUP CONSISTING OF HYDROCORTISONE, ACETAMINOPHINE, ALLANTOIN, GLYCYRRHETIC STEARYL, AND DERMATOLOGICALLY ACCEPTABLE SALTS OF GLYCYRRHIZIC ACID. | SHISEIDO COMPANY, LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5686086-A | VITAMIN A, POLYETHERSILOXANE COPOLYMER | SHISEIDO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0610511-A1 | COMPOSITION FOR DERMATOLOGIC PREPARATION | SHISEIDO COMPANY LIMITED (JP) | 1994-08-17 | — | — | EP | disclosed |
| EP-0098566-A2 | Corticoids-containing preparation for topical application | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-01-18 | — | — | EP | disclosed |