SCHEMBL391631

SCHEMBL391631

CCCCC(=O)OCC(=O)[C@@]1(OC(C)=O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3C(O)C[C@@]21C

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 8/20 0.74
▸ HIF1A Q16665 7/20 0.74
▸ NR3C1 P04150 7/20 0.74
▸ LMNA P02545 3/20 0.74
▸ CYP3A4 P08684 2/20 0.74
▸ USP2 O75604 1/20 0.74
▸ CYP2D6 P10635 1/20 0.74
▸ CYP2C9 P11712 1/20 0.74
▸ ABCB11 O95342 2/20 0.61
▸ NR1I2 O75469 2/20 0.61
▸ ABCC3 O15438 1/20 0.61
▸ AR P10275 2/20 0.57
▸ CHRM1 P11229 1/20 0.57
▸ NR3C2 P08235 4/20 0.57
▸ HSD17B10 Q99714 2/20 0.57
▸ TNF P01375 1/20 0.57
▸ IL6 P05231 1/20 0.57
▸ SERPINA6 P08185 1/20 0.57
▸ GLUL P15104 1/20 0.57
▸ ADAM17 P78536 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2252725 0.96 NR3C1 (0.75) PGRHIF1ANR3C1LMNACYP3A4
Prednisolone Valerate Acetate SCHEMBL375318 0.94 PGR (0.72) PGRHIF1ANR3C1LMNACYP3A4
Prednisolone Valerate Acetate SCHEMBL375319 0.94 PGR (0.72) PGRHIF1ANR3C1LMNACYP3A4
SCHEMBL730945 0.94 HIF1A (0.79) PGRHIF1ANR3C1LMNACYP3A4
Prednisolone Valerate Acetate SCHEMBL14339603 0.94 PGR (0.72) PGRHIF1ANR3C1LMNACYP3A4
SCHEMBL11425603 0.92 HIF1A (0.77) PGRHIF1ANR3C1LMNACYP3A4
SCHEMBL11428048 0.92 HIF1A (0.80) PGRHIF1ANR3C1LMNACYP3A4
SCHEMBL11438434 0.92 PGR (0.87) PGRHIF1ANR3C1LMNACYP3A4
SCHEMBL11426076 0.92 HIF1A (0.78) PGRHIF1ANR3C1LMNACYP3A4
SCHEMBL2299113 0.91 PGR (0.78) PGRHIF1ANR3C1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 585 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4744657-A1 THERAPEUTIC AGENT FOR HUMAN GRAFT VERSUS HOST DISEASE AND COMBINATION THEREOF National University Corporation Okayama University (JP) 2026-05-20 — — EP claimed
US-20250332120-A1 COMPOSITION FOR EXTERNAL PREPARATION KAO CORPORATION (JP) 2025-10-30 — — US claimed
US-20250170069-A1 NANOPREPARATION FOR JOINT ANALGESIA, AND PREPARATION METHOD AND USE THEREOF XIANGYA HOSPITAL CENTRAL SOUTH UNIV (CN) 2025-05-29 — — US claimed
CN-119894520-A External skin preparation composition 志瑞亚新药工业株式会社 2025-04-25 — — CN claimed
EP-4470532-A1 NANO PREPARATION FOR JOINT ANALGESIA, AND PREPARATION METHOD THEREFOR AND USE THEREOF Xiangya Hospital, Central South University (CN) 2024-12-04 — — EP claimed
WO-2024058193-A1 COMPOSITION FOR EXTERNAL PREPARATION FOR SKIN ゼリア新薬工業株式会社 2024-03-21 — — WO claimed
CN-114126574-B External preparation for skin 花王株式会社 2023-11-21 — — CN claimed
US-11376262-B2 Method of treating an inflammatory or infectious disease ACTIVUS PHARMA CO., LTD. (JP) 2022-07-05 — — US claimed
CN-107613985-B Aqueous suspensions of nanoparticles containing glucocorticoids 株式会社活效制药 2021-05-25 — — CN claimed
CN-109608511-B Chemical synthesis process of prednisolone valerate acetate 上海新华联制药有限公司 2021-05-04 — — CN claimed
US-9095512-B2 Method for producing spherical base granules comprising hardly water-soluble drug ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-08-04 — — US claimed
CN-103432584-A Cooling and itching relieving composition and paper towel employing same GOLD HONG YE PAPER CO LTD 2013-12-11 — — CN claimed
US-8101207-B2 Composition containing medicine extremely slightly soluble in water and method for preparation thereof KOWA CO., LTD. (JP) 2012-01-24 — — US claimed
US-20090012051-A1 EXTERNAL PREPARATION KYOWA HAKKO KOGYO CO., LTD. (JP) 2009-01-08 — — US claimed
US-20070287689-A1 Therapeutic And/Or Preventive Agents For Chronic Skin Diseases KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-12-13 — — US claimed
CN-101053552-A O/W type emulsification preparation containing prednisolone valerate acetate KOWA CO (JP) 2007-10-17 — — CN claimed
EP-1810692-A1 REMEDIES/PREVENTIVES FOR CHRONIC SKIN DISEASE KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-07-25 — — EP claimed
US-20070128273-A1 Composition containing medicine extremely slightly soluble in water and method for preparation thereof KOWA CO., LTD. (JP) 2007-06-07 — — US claimed
WO-1997027862-A1 SUPPLEMENTATION OF GLUCOCORTICOIDS BELLARA MEDICAL PRODUCTS LIMITED (AU) 1997-08-07 — — WO claimed
US-5236906-A Adrenocortical hormone and hyaluronic acid; skin diseases TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-08-17 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012051-A1 EXTERNAL PREPARATION CYP4A11, CYP46A1, CYP11B2 PGR 2297/4885HIF1A 1229/4885NR3C1 556/4885
US-20070287689-A1 Therapeutic And/Or Preventive Agents For Chronic Skin Diseases PDE4A, PDE3B, PDE2A PGR 1575/4885HIF1A 2269/4885NR3C1 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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