Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MET | P08581 | 2/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9909102 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HPGDCASP1HSD17B10HTT | |
| SCHEMBL7817348 | 0.72 | MET (0.59) | ALDH1A1HPGDCASP1HSD17B10KDM4E | |
| SCHEMBL14580923 | 0.71 | — | — | |
| SCHEMBL9909095 | 0.71 | ALDH1A1 (0.44) | ALDH1A1HPGDCASP1HSD17B10HTT | |
| SCHEMBL9906911 | 0.69 | ALDH1A1 (0.35) | ALDH1A1HPGDCASP1HSD17B10HTT | |
| SCHEMBL18413331 | 0.69 | KDM4E (0.30) | ALDH1A1HPGDHSD17B10KDM4EMAPK1 | |
| SCHEMBL7820657 | 0.68 | KDM4E (0.61) | ALDH1A1HPGDCASP1HSD17B10KDM4E | |
| SCHEMBL8645927 | 0.63 | LMNA (0.31) | ALDH1A1HPGDCASP1HSD17B10HTT | |
| SCHEMBL12433065 | 0.63 | LMNA (0.34) | ALDH1A1HPGDHSD17B10HTTKDM4E | |
| SCHEMBL11792839 | 0.59 | ALDH1A1 (0.42) | ALDH1A1HSD17B10HTTKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578177-B1 | Heat-resistant negative photoresist composition, photosensitive substrate, and process for forming negative pattern | NITTO DENKO CORP (JP) | 1997-03-05 | — | — | EP | claimed |
| EP-0578177-A2 | Heat-resistant negative photoresist composition, photosensitive substrate, and process for forming negative pattern | NITTO DENKO CORPORATION (JP) | 1994-01-12 | — | — | EP | claimed |
| US-8728705-B2 | Negative photosensitive material, photosensitive board employing the negative photosensitive material, and negative pattern forming method | NITTO DENKO CORPORATION (JP) | 2014-05-20 | — | — | US | disclosed |
| US-20130118788-A1 | POLYIMIDE PRECURSOR COMPOSITION, AND WIRING CIRCUIT BOARD EMPLOYING THE COMPOSITION | NITTO DENKO CORPORATION (JP) | 2013-05-16 | — | — | US | disclosed |
| EP-2121608-B1 | DIHYDROPYRIDINE DERIVATIVES USEFUL AS PROTEIN KINASE INHIBITORS | BAYER IP GMBH (DE) | 2012-11-14 | — | — | EP | disclosed |
| US-8198456-B2 | e.g. 1,4-dihydro-4-(1H-indazol-5-yl)-2,6-dimethyl-3,5-pyridinedicarbonitrile; c-Met tyrosine kinase inhibitor; antitumor agent; lung, liver, gastric and breast solid tumors; pancreatic cancer, glioma, and hepatocellular carcinoma | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-06-12 | — | — | US | disclosed |
| US-20100304298-A1 | NEGATIVE PHOTOSENSITIVE MATERIAL, PHOTOSENSITIVE BOARD EMPLOYING THE NEGATIVE PHOTOSENSITIVE MATERIAL, AND NEGATIVE PATTERN FORMING METHOD | NITTO DENKO CORPORATION (JP) | 2010-12-02 | — | — | US | disclosed |
| US-20080176833-A1 | DIHYDROPYRIDINE DERIVATIVES AS USEFUL AS PROTEIN KINASE INHIBITORS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-07-24 | — | — | US | disclosed |
| WO-2008071451-A1 | DIHYDROPYRIDINE DERIVATIVES USEFUL AS PROTEIN KINASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-06-19 | — | — | WO | disclosed |
| US-5851736-A | Heat-resistant photoresist composition, photosensitive substrate, and process for forming heat-resistant positive or negative pattern | NITTO DENKO CORPORATION (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0578177-B1 | Heat-resistant negative photoresist composition, photosensitive substrate, and process for forming negative pattern | NITTO DENKO CORP (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0578177-A2 | Heat-resistant negative photoresist composition, photosensitive substrate, and process for forming negative pattern | NITTO DENKO CORPORATION (JP) | 1994-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176833-A1 | DIHYDROPYRIDINE DERIVATIVES AS USEFUL AS PROTEIN KINASE INHIBITORS | MET, DMPK, RET | ALDH1A1 1341/4885HPGD 2338/4885CASP1 3706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.