SCHEMBL3754193

SCHEMBL3754193

[CH2]Oc1ccc(F)c(Br)c1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
VCP P55072 1/20 0.34
KDM4E B2RXH2 1/20 0.33
EPAS1 Q99814 1/20 0.32
SOS1 Q07889 1/20 0.32
IDO1 P14902 1/20 0.31
NPSR1 Q6W5P4 2/20 0.30
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30180094 0.79 CA12 (0.46) KDM4ETSHRCYP1A2NFE2L2
SCHEMBL1042775 0.79 CA12 (0.46) KDM4ETSHRCYP1A2NFE2L2
SCHEMBL4800898 0.78 NPC1 (0.33)
SCHEMBL1547827 0.78 SOS1 (0.42) SOS1NFE2L2
SCHEMBL17597847 0.76 VCP (0.33) VCPKDM4EEPAS1SOS1IDO1
SCHEMBL30018924 0.74 GPR3 (0.46) LMNACYP1A2CYP2C9
SCHEMBL15718212 0.74 GPR3 (0.46) LMNACYP1A2CYP2C9
SCHEMBL29184353 0.74 VCP (0.33) VCPKDM4EEPAS1SOS1IDO1
SCHEMBL15016881 0.74 ALOX15 (0.43) KDM4EEPAS1NPSR1LMNATSHR
SCHEMBL29888754 0.74 ALOX15 (0.43) KDM4EEPAS1NPSR1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426631-B2 Fungicidal compounds, method for the production thereof, and use thereof to combat damaging fungi, and agents comprising the same BASF SE (DE) 2013-04-23 US disclosed
US-20100304966-A1 Fungicidal Compounds, Method For the Production Thereof, And Use Thereof To Combat Damaging Fungi, And Agents Comprising The Same BASF SE (DE) 2010-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100304966-A1 Fungicidal Compounds, Method For the Production Thereof, And Use Thereof To Combat Damaging Fungi, And Agents Comprising The Same CYP51A1, ERG28, CAT VCP 827/4885KDM4E 856/4885EPAS1 3550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.