Ether

Ether

SCHEMBL3756308

CCOCC.Oc1ccc(-c2ccc(O)c(Cl)c2)cc1Cl

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 4/20 0.57
ESR1 P03372 2/20 0.52
HSD17B1 P14061 3/20 0.47
HSD17B2 P37059 3/20 0.47
TSHR P16473 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CYP17A1 P05093 1/20 0.44
CYP3A4 P08684 1/20 0.44
HSP90AA1 P07900 2/20 0.42
HSP90AB1 P08238 2/20 0.42
CA2 P00918 2/20 0.42
CA1 P00915 1/20 0.42
HDAC2 Q92769 1/20 0.41
AR P10275 1/20 0.41
ALOX5 P09917 1/20 0.41
AHR P35869 1/20 0.39
APP P05067 1/20 0.39
JAK2 O60674 1/20 0.39
JAK1 P23458 1/20 0.39
TYK2 P29597 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278316 0.82 ESR2 (0.77) ESR2ESR1HSD17B1HSD17B2TSHR
SCHEMBL29911026 0.82 ESR2 (0.77) ESR2ESR1HSD17B1HSD17B2TSHR
SCHEMBL28202577 0.82 ESR2 (0.77) ESR2ESR1HSD17B1HSD17B2TSHR
Methane SCHEMBL10594573 0.80 ESR2 (0.74) ESR2ESR1HSD17B1HSD17B2TSHR
SCHEMBL11785610 0.78 HSD17B1 (0.59) ESR2ESR1HSD17B1HSD17B2TSHR
Ether SCHEMBL2809011 0.78 HSD17B1 (0.53) ESR2ESR1HSD17B1HSD17B2AR
SCHEMBL10907449 0.77 CA2 (0.49) HSD17B2TSHRHSD17B10CYP3A4HSP90AA1
SCHEMBL7906570 0.76 AHR (0.70) ESR2ESR1HSD17B1HSD17B2TSHR
Ether SCHEMBL2810859 0.76 ALDH1A1 (0.57) TSHRHSD17B10CYP3A4HSP90AA1CA2
SCHEMBL12123510 0.75 ESR2 (0.61) ESR2ESR1HSD17B1HSD17B2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2500382-B1 Resin composition, and molded article produced from the same UNITIKA LTD (JP) 2014-09-10 EP disclosed
US-8415008-B2 Resin composition, and molded article produced from the same UNITIKA LTD. (JP) 2013-04-09 US disclosed
EP-2500382-A2 Resin composition, and molded article produced from the same Unitika, Ltd. (JP) 2012-09-19 EP disclosed
US-20100028657-A1 Resin composition, and molded article produced from the same UNITIKA LTD. (JP) 2010-02-04 US disclosed
EP-2113532-A1 RESIN COMPOSITION, AND MOLDED ARTICLE PRODUCED FROM THE SAME Unitika, Ltd. (JP) 2009-11-04 EP disclosed