Dimpylate

Dimpylate

SCHEMBL3756703

CCOP(=S)(OCC)Oc1cc(C)nc(C(C)C)n1.Cc1cc(OP(O)(O)=S)nc(C(C)C)n1

nearest known ligand 0.87

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.87
TSHR P16473 3/20 0.87
CYP3A4 P08684 2/20 0.87
HSD17B10 Q99714 2/20 0.87
TP53 P04637 1/20 0.87
ACHE P22303 1/20 0.87
TDP1 Q9NUW8 4/20 0.54
MAPT P10636 4/20 0.41
KMT2A Q03164 2/20 0.38
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
MAPK1 P28482 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
KDM4E B2RXH2 2/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimpylate SCHEMBL9812732 0.95 ALDH1A1 (0.92) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL17453 0.93 ALDH1A1 (1.00) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL6118696 0.93 ALDH1A1 (1.00) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL27440593 0.92 ALDH1A1 (0.87) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL28706929 0.92 ALDH1A1 (0.92) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL4747660 0.92 ALDH1A1 (0.92) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL1344740 0.92 ALDH1A1 (0.97) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL6214077 0.92 ALDH1A1 (0.97) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL3841005 0.92 ALDH1A1 (0.97) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL6753267 0.92 ALDH1A1 (0.97) ALDH1A1TSHRCYP3A4HSD17B10TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100015191-A1 DEVICE AND METHOD FOR CONTROLLING INSECTS WYETH (US) 2010-01-21 US disclosed
US-5750467-A WON'T WASH OFF, ULTRAVIOLET STABLE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1998-05-12 US disclosed