Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193253 | 0.79 | L3MBTL1 (0.44) | KDM5AKDM4CHTTCYP1A2TSHR | |
| SCHEMBL9741854 | 0.77 | HTT (0.63) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL2193763 | 0.71 | ATP4A (0.55) | ALDH1A1KDM5AKDM4CHTTCYP1A2 | |
| SCHEMBL795384 | 0.71 | ATP4A (0.62) | CYP1A2CYP2C9CYP3A4CYP2C19MAPK14 | |
| SCHEMBL11464701 | 0.70 | KDM4E (0.56) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL1444060 | 0.69 | ENPP2 (0.65) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| Hydrochloric Acid SCHEMBL11365039 | 0.69 | KDM4E (0.55) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| Hydrochloric Acid SCHEMBL2049884 | 0.68 | ENPP2 (0.64) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL11363269 | 0.66 | HTT (0.59) | ALDH1A1KDM4EHPGDHSD17B10KDM5A | |
| SCHEMBL11361275 | 0.65 | HTT (0.57) | ALDH1A1KDM4EHPGDHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298566-A1 | PROCESS FOR THE PREPARATION OF PALIPERIDONE AND ITS INTERMEDIATES | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2010-11-25 | — | — | US | claimed |
| WO-2009060297-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF PALIPERIDONE AND ITS INTERMEDIATES | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2009-05-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298566-A1 | PROCESS FOR THE PREPARATION OF PALIPERIDONE AND ITS INTERMEDIATES | AVPR2, AVPR1A, AVPR1B | ALDH1A1 355/4885KDM4E 2560/4885HPGD 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.