SCHEMBL375704

SCHEMBL375704

CCCCCCCCCCCCCCO[Si](CCC(C)S)(OCCCCCCCCCCCCCC)OCCCCCCCCCCCCCC

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LPAR2 Q9HBW0 3/20 0.33
LPAR3 Q9UBY5 3/20 0.33
DNM1 Q05193 3/20 0.32
SPHK1 Q9NYA1 1/20 0.31
TSHR P16473 2/20 0.31
USP2 O75604 1/20 0.31
HTT P42858 2/20 0.31
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.31
OPRM1 P35372 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375624 1.00 LPAR2 (0.33) LPAR2LPAR3DNM1SPHK1TSHR
SCHEMBL375590 1.00 LPAR2 (0.33) LPAR2LPAR3DNM1SPHK1TSHR
SCHEMBL375792 1.00 LPAR2 (0.33) LPAR2LPAR3DNM1SPHK1TSHR
SCHEMBL375558 1.00 LPAR2 (0.33) LPAR2LPAR3DNM1SPHK1TSHR
SCHEMBL30186444 0.88 SMPD1 (0.31) OPRM1
SCHEMBL375352 0.84
SCHEMBL2552953 0.81 OPRM1 (0.48) LPAR2LPAR3DNM1SPHK1HTT
SCHEMBL2555162 0.81 OPRM1 (0.48) LPAR2LPAR3DNM1SPHK1HTT
SCHEMBL2552500 0.81 OPRM1 (0.48) LPAR2LPAR3DNM1SPHK1HTT
SCHEMBL5155605 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7518009-B2 Process for preparing mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2009-04-14 US claimed
US-20060252952-A1 Process for preparing mercaptoorganyl (alkoxysilanes) DEGUSSA AG (DE) 2006-11-09 US claimed
US-12139635-B2 Coatings for waterproofing electronic components HENKEL AG & CO. KGAA (DE) 2024-11-12 US disclosed
US-20220002559-A1 COATINGS FOR WATERPROOFING ELECTRONIC COMPONENTS HENKEL AG & CO. KGAA (DE) 2022-01-06 US disclosed
WO-2020197963-A1 COATINGS FOR WATERPROOFING ELECTRONIC COMPONENTS HENKEL AG & CO. KGAA (DE) 2020-10-01 WO disclosed
US-20140005432-A1 PROCESS FOR PREPARING ORGANOSILANES EVONIK DEGUSSA GMBH (DE) 2014-01-02 US disclosed
EP-2408785-A1 PROCESS FOR PREPARING ORGANOSILANES Evonik Degussa GmbH (DE) 2012-01-25 EP disclosed
WO-2010105434-A1 PROCESS FOR PREPARING ORGANOSILANES EVONIK DEGUSSA GMBH (DE) 2010-09-23 WO disclosed
US-7518009-B2 Process for preparing mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2009-04-14 US disclosed
US-7501534-B2 Process for the preparation of organosilanes DEGUSSA AG (DE) 2009-03-10 US disclosed
US-7339067-B2 Process for producing mercaptoorganyl (alkoxysilane) EVONIK DEGUSSA GMBH (DE) 2008-03-04 US disclosed
EP-1538152-B1 Process for the preparation of (mercaptoorganyl)-alkoxysilanen DEGUSSA (DE) 2006-03-22 EP disclosed
EP-1634884-A1 Process for preparing mercaptoorganyl alkoxy silanes Degussa GmbH (DE) 2006-03-15 EP disclosed
US-20060052621-A1 Process for producing mercaptoorganyl (alkoxysilane) EVONIK DEGUSSA GMBH (DE) 2006-03-09 US disclosed
US-20060052622-A1 Process for the preparation of mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2006-03-09 US disclosed
US-6995280-B2 Process for preparing (mercaptoorganyl)alkoxysilanes DEGUSSA AG (DE) 2006-02-07 US disclosed
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 US disclosed
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 US disclosed
EP-1538152-A1 Process for the preparation of (mercaptoorganyl)-alkoxysilanen Degussa AG (DE) 2005-06-08 EP disclosed
EP-1529782-A1 Process for preparing mercaptoorganyl alkoxy silanes Degussa AG (DE) 2005-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes ADH1C, ADH1A, MPST LPAR2 2800/4885LPAR3 3214/4885DNM1 2435/4885
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes MPST, ADH1A, ADH1C LPAR2 2555/4885LPAR3 2985/4885DNM1 3260/4885
US-20140005432-A1 PROCESS FOR PREPARING ORGANOSILANES MPST, STS, CYP2S1 LPAR2 1773/4885LPAR3 3000/4885DNM1 4873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.