Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 5/20 | 0.67 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.67 |
| ▸ | CCR5 | P51681 | 14/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13171413 | 1.00 | UBE2M (0.67) | UBE2MDCUN1D1CCR5KCNH2LMNA | |
| SCHEMBL3765239 | 0.96 | CCR5 (0.65) | UBE2MDCUN1D1CCR5KCNH2 | |
| SCHEMBL3765311 | 0.91 | CCR5 (0.68) | UBE2MDCUN1D1CCR5KCNH2 | |
| SCHEMBL13878217 | 0.91 | CCR5 (0.68) | UBE2MDCUN1D1CCR5KCNH2 | |
| SCHEMBL13192591 | 0.90 | CCR5 (0.67) | UBE2MDCUN1D1CCR5KCNH2 | |
| SCHEMBL13081247 | 0.90 | CCR5 (0.67) | UBE2MDCUN1D1CCR5KCNH2 | |
| SCHEMBL13081249 | 0.89 | CCR5 (0.67) | UBE2MDCUN1D1CCR5KCNH2 | |
| SCHEMBL3755242 | 0.88 | CCR5 (0.73) | UBE2MDCUN1D1CCR5KCNH2 | |
| SCHEMBL3755235 | 0.88 | CCR5 (0.73) | UBE2MDCUN1D1CCR5KCNH2 | |
| SCHEMBL3763555 | 0.88 | CCR5 (0.66) | UBE2MDCUN1D1CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2010-11-25 | — | — | US | disclosed |
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2010-11-25 | — | — | US | disclosed |
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2010-11-25 | — | — | US | disclosed |
| US-7790747-B2 | Chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2010-09-07 | — | — | US | disclosed |
| US-7790747-B2 | Chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2010-09-07 | — | — | US | disclosed |
| US-7790747-B2 | Chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090099205-A1 | Chemokine receptor binding compounds | GENZYME CORPORATION | 2009-04-16 | — | — | US | disclosed |
| US-20090099205-A1 | Chemokine receptor binding compounds | GENZYME CORPORATION | 2009-04-16 | — | — | US | disclosed |
| US-20090099205-A1 | Chemokine receptor binding compounds | GENZYME CORPORATION | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | CCR5, CXCR3, CCL5 | UBE2M 4562/4885DCUN1D1 3581/4885CCR5 1/4885 |
| US-20090099205-A1 | Chemokine receptor binding compounds | CCR5, CXCR3, CCL5 | UBE2M 4562/4885DCUN1D1 3581/4885CCR5 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.