SCHEMBL3757630

SCHEMBL3757630

CC(CCOC(=O)c1ccc(C(=O)OCCC(C)CC(C)(C)C)cc1)CC(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.50
PKM P14618 2/20 0.50
HSD17B10 Q99714 1/20 0.50
EGFR P00533 1/20 0.48
TSHR P16473 3/20 0.45
ESR1 P03372 2/20 0.45
ALDH1A1 P00352 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
CHRM1 P11229 1/20 0.45
SLC6A2 P23975 1/20 0.45
KDR P35968 1/20 0.45
RAB9A P51151 2/20 0.44
MAPT P10636 2/20 0.44
SCN1A P35498 1/20 0.43
SCN2A Q99250 1/20 0.43
SCN3A Q9NY46 1/20 0.43
LMNA P02545 3/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 2/20 0.42
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8615590 0.94 MAPT (0.54) MAPK1PKMHSD17B10EGFRTSHR
SCHEMBL6023299 0.93 SCN1A (0.55) MAPK1PKMHSD17B10EGFRTSHR
SCHEMBL574291 0.92 LMNA (0.54) MAPK1PKMHSD17B10EGFRTSHR
SCHEMBL28895855 0.88 EGFR (0.47) MAPK1PKMHSD17B10EGFRTSHR
SCHEMBL5826734 0.87 EGFR (0.50) MAPK1PKMHSD17B10EGFRTSHR
SCHEMBL2807375 0.84 ALDH1A1 (0.53) MAPK1HSD17B10EGFRTSHRALDH1A1
SCHEMBL29358453 0.84 ALDH1A1 (0.53) MAPK1HSD17B10EGFRTSHRALDH1A1
SCHEMBL16194376 0.84 TDP1 (0.48) MAPK1PKMHSD17B10EGFRTSHR
SCHEMBL5826822 0.83 EGFR (0.54) MAPK1PKMHSD17B10EGFRTSHR
SCHEMBL4734380 0.83 SERPINE1 (0.58) PKMEGFRESR1ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329796-B2 Mixtures of diisononyl esters of terephthalic acid, method for the production thereof and use thereof EVONIK OXENO GMBH (DE) 2012-12-11 US disclosed
US-20100305255-A1 MIXTURES OF DIISONONYL ESTERS OF TEREPHTHALIC ACID, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF EVONIK OXENO GMBH (DE) 2010-12-02 US disclosed
EP-0880495-A1 HIGH STABILITY AND LOW METALS ESTERS BASED ON 3,5,5-TRIMETHYL-1-HEXANOL EXXON CHEMICAL PATENTS INC. (US) 1998-12-02 EP disclosed
US-5798319-A SYNTHETIC ESTER COMPOSITION EXHIBITING THERMAL AND OXIDATIVE STABILITY EXXON CHEMICAL PATENTS INC. (US) 1998-08-25 US disclosed
WO-1997026238-A1 HIGH STABILITY AND LOW METALS ESTERS BASED ON 3,5,5-TRIMETHYL-1-HEXANOL EXXON CHEMICAL PATENTS INC. (US) 1997-07-24 WO disclosed