SCHEMBL574291

SCHEMBL574291

CC(CCOC(=O)c1ccccc1)CC(C)(C)C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
TDP1 Q9NUW8 4/20 0.53
MAPK1 P28482 2/20 0.47
HIF1A Q16665 1/20 0.47
ADRB2 P07550 2/20 0.47
ADRB1 P08588 2/20 0.47
ADRB3 P13945 2/20 0.47
ALDH1A1 P00352 2/20 0.46
EGFR P00533 1/20 0.46
PKM P14618 2/20 0.44
TSHR P16473 2/20 0.44
SLC6A3 Q01959 2/20 0.44
SLC6A2 P23975 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HTR1A P08908 1/20 0.43
CYP2D6 P10635 1/20 0.43
SCN1A P35498 1/20 0.43
SCN5A Q14524 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3757630 0.92 MAPK1 (0.50) LMNATDP1MAPK1ALDH1A1EGFR
SCHEMBL16194376 0.91 TDP1 (0.48) LMNATDP1MAPK1HIF1AADRB2
SCHEMBL28895855 0.90 EGFR (0.47) LMNATDP1MAPK1ADRB2ADRB1
SCHEMBL8615590 0.90 MAPT (0.54) LMNATDP1MAPK1ALDH1A1EGFR
SCHEMBL28895857 0.88 EGFR (0.44) LMNATDP1ADRB1ALDH1A1EGFR
SCHEMBL223683 0.87 LMNA (0.65) LMNATDP1MAPK1HIF1AADRB2
SCHEMBL29358453 0.86 ALDH1A1 (0.53) LMNATDP1MAPK1ALDH1A1EGFR
SCHEMBL2807375 0.86 ALDH1A1 (0.53) LMNATDP1MAPK1ALDH1A1EGFR
SCHEMBL6023299 0.85 SCN1A (0.55) LMNATDP1MAPK1ADRB2ADRB1
SCHEMBL9856613 0.85 LMNA (0.54) LMNATDP1MAPK1HIF1AADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492066-B2 Toner compositions and processes XEROX CORPORATION (US) 2013-07-23 US claimed
US-20120244470-A1 TONER COMPOSITIONS AND PROCESSES XEROX CORPORATION (US) 2012-09-27 US claimed
US-7736831-B2 Emulsion/aggregation process using coalescent aid agents XEROX CORPORATION (US) 2010-06-15 US claimed
US-20080063965-A1 Emulsion/aggregation processes using coalescent aid agents XEROX CORPORATION (US) 2008-03-13 US claimed
US-11692069-B2 Method for making fluorocarbon free emulsions without using traditional surfactants/emulsifiers by emulsifying alkoxysilanes or other non-water soluble hydrophobizing agents using amino functional siloxanes and the uses thereof ORGANOCLICK AB (SE) 2023-07-04 US disclosed
CN-107282939-B Silver nanoparticle-sulfonated polyester composite powder and preparation method thereof 施乐公司 2022-04-29 CN disclosed
CN-107286596-B Styrene-based polymer-coated silver nanoparticle-sulfonated polyester composite powder and preparation method thereof 施乐公司 2021-06-04 CN disclosed
EP-2721100-B1 ENVIRONMENTALLY FRIENDLY COALESCING AGENTS PTT GLOBAL CHEMICAL PUBLIC CO LTD (TH) 2020-08-19 EP disclosed
EP-3266908-B1 ANTI-BACTERIAL METALLO IONOMER POLYMER NANOCOMPOSITE FILAMENTS AND METHODS OF MAKING THE SAME XEROX CORP (US) 2020-05-06 EP disclosed
CN-107287692-B Polymer coated sulfonated polyester-silver nanoparticle composite filament and preparation method thereof 施乐公司 2020-03-31 CN disclosed
CN-107287681-B Silver polyester-sulfonated nano-particle composite filament and preparation method thereof 施乐公司 2020-02-28 CN disclosed
EP-3266613-B1 ANTI-BACTERIAL METALLO IONOMER POLYMER COMPOSITE POWDERS AND METHODS OF MAKING THE SAME XEROX CORP (US) 2019-10-16 EP disclosed
US-7445790-B2 External preparations for skin SHISEIDO COMPANY, LTD. (JP) 2008-11-04 US disclosed
US-7445790-B2 External preparations for skin SHISEIDO COMPANY, LTD. (JP) 2008-11-04 US disclosed
US-20080063965-A1 Emulsion/aggregation processes using coalescent aid agents XEROX CORPORATION (US) 2008-03-13 US disclosed
US-7323588-B2 Isononyl benzoates and their use OXENO OLEFINCHEMIE GMBH (DE) 2008-01-29 US disclosed
US-20070010599-A1 Use of isononyl benzoate as a film-forming agent OXENO OLEFINCHEMIE GMBH (DE) 2007-01-11 US disclosed
US-20050180931-A1 External preparations for skin SHISEIDO COMPANY, LTD. (JP) 2005-08-18 US disclosed
EP-1550429-A1 EXTERNAL PREPARATIONS FOR SKIN SHISEIDO COMPANY, LTD. (JP) 2005-07-06 EP disclosed
US-20040015007-A1 Isononyl benzoates and their use OXENO OLEFINCHEMIE GMBH (DE) 2004-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050180931-A1 External preparations for skin CUTA, HRH1, CYP24A1 LMNA 1962/4885TDP1 4101/4885MAPK1 3951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.