SCHEMBL6023299

SCHEMBL6023299

CC(CCOC(=O)c1ccc(N)cc1)CC(C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 2/20 0.55
SCN2A Q99250 2/20 0.55
SCN3A Q9NY46 2/20 0.55
LMNA P02545 3/20 0.54
CYP1A2 P05177 3/20 0.54
CYP3A4 P08684 3/20 0.54
TSHR P16473 3/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
PDE4D Q08499 1/20 0.54
PHLPP2 Q6ZVD8 1/20 0.52
MAOA P21397 2/20 0.51
RAB9A P51151 3/20 0.51
NPC1 O15118 2/20 0.51
ALDH1A1 P00352 2/20 0.51
MAPT P10636 1/20 0.51
CYP2D6 P10635 2/20 0.50
HTR3A P46098 1/20 0.50
HRH3 Q9Y5N1 1/20 0.50
ADRB2 P07550 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3757630 0.93 MAPK1 (0.50) SCN1ASCN2ASCN3ALMNACYP1A2
SCHEMBL8615590 0.87 MAPT (0.54) SCN1ASCN2ASCN3ALMNACYP1A2
SCHEMBL574291 0.85 LMNA (0.54) SCN1ASCN2ASCN3ALMNATSHR
SCHEMBL7142990 0.84 NPC1 (0.55) SCN1ASCN2ASCN3ALMNACYP1A2
SCHEMBL6748144 0.82 SCN1A (0.68) SCN1ASCN2ASCN3ALMNACYP1A2
SCHEMBL28895855 0.81 EGFR (0.47) LMNATSHRALDH1A1ADRB2ADRB1
SCHEMBL5826734 0.81 EGFR (0.50) TSHRRAB9AALDH1A1MAPTGAA
SCHEMBL15449675 0.80 SCN1A (0.58) SCN1ASCN2ASCN3ALMNACYP1A2
SCHEMBL6024231 0.80 SCN1A (0.58) SCN1ASCN2ASCN3ALMNACYP1A2
SCHEMBL4716884 0.80 SCN1A (0.58) SCN1ASCN2ASCN3ALMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1286651-B1 USE OF AMINOBENZOIC ACIDS IN COMPOSITIONS WITH PERFUMES QUEST INT SERV BV (NL) 2006-08-02 EP claimed
WO-2007006807-A1 NEW DERIVATIVES OF HEPTAAZAPHENALENE, METHODS FOR OBTAINING THEM, AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION ISDIN, S.A. (ES) 2007-01-18 WO disclosed
US-7129204-B2 Perfumes QUEST INTERNATIONAL SERVICES B.V. (NL) 2006-10-31 US disclosed
EP-1286651-B1 USE OF AMINOBENZOIC ACIDS IN COMPOSITIONS WITH PERFUMES QUEST INT SERV BV (NL) 2006-08-02 EP disclosed
US-20030199422-A1 Perfumes QUEST INTERNATIONAL SERVICES B.V. (NL) 2003-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199422-A1 Perfumes PAH, PIR, TRPA1 SCN1A 3625/4885SCN2A 3756/4885SCN3A 3945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.