Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | CCR5 | P51681 | 7/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3762699 | 1.00 | MCHR1 (0.42) | MCHR1HRH3TAAR1BCHEACHE | |
| SCHEMBL3762693 | 0.82 | MCHR1 (0.40) | MCHR1HRH3CCR5KCNH2AVPR1A | |
| SCHEMBL3758106 | 0.82 | MCHR1 (0.40) | MCHR1HRH3CCR5KCNH2AVPR1A | |
| SCHEMBL3832667 | 0.82 | CCR5 (0.47) | MCHR1CCR5KCNH2 | |
| SCHEMBL3832661 | 0.82 | CCR5 (0.47) | MCHR1CCR5KCNH2 | |
| SCHEMBL3757433 | 0.77 | CCR5 (0.45) | MCHR1CCR5KCNH2 | |
| SCHEMBL3757430 | 0.77 | CCR5 (0.45) | MCHR1CCR5KCNH2 | |
| SCHEMBL3761298 | 0.77 | ACHE (0.58) | TAAR1BCHEACHEBACE1 | |
| SCHEMBL3759484 | 0.77 | DPP4 (0.32) | HRH3 | |
| SCHEMBL3833501 | 0.76 | CCR5 (0.36) | MCHR1CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2010-11-25 | — | — | US | disclosed |
| US-7790747-B2 | Chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090099205-A1 | Chemokine receptor binding compounds | GENZYME CORPORATION | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | CCR5, CXCR3, CCL5 | MCHR1 340/4885HRH3 703/4885TAAR1 853/4885 |
| US-20090099205-A1 | Chemokine receptor binding compounds | CCR5, CXCR3, CCL5 | MCHR1 340/4885HRH3 703/4885TAAR1 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.