Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 5/20 | 0.91 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.91 |
| ▸ | ESR1 | P03372 | 4/20 | 0.91 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.91 |
| ▸ | NQO2 | P16083 | 4/20 | 0.91 |
| ▸ | AHR | P35869 | 3/20 | 0.91 |
| ▸ | TTR | P02766 | 3/20 | 0.91 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.91 |
| ▸ | ABL1 | P00519 | 2/20 | 0.91 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.91 |
| ▸ | BCR | P11274 | 2/20 | 0.91 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.91 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.91 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.91 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.91 |
| ▸ | TUBB | P07437 | 1/20 | 0.91 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.91 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.91 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.91 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13443549 | 1.00 | CYP1A1 (0.91) | CYP1A1CYP1B1ESR1PTGS2NQO2 | |
| Trismethoxyresveratrol SCHEMBL918739 | 0.95 | CYP1A1 (1.00) | CYP1A1CYP1B1ESR1PTGS2NQO2 | |
| 8Z-3,4',5-Trimethoxystilbene SCHEMBL1006207 | 0.95 | CYP1A1 (1.00) | CYP1A1CYP1B1ESR1PTGS2NQO2 | |
| Trismethoxyresveratrol SCHEMBL918740 | 0.95 | CYP1A1 (1.00) | CYP1A1CYP1B1ESR1PTGS2NQO2 | |
| SCHEMBL9177232 | 0.95 | TUBB1 (0.83) | CYP1A1CYP1B1ESR1PTGS2NQO2 | |
| SCHEMBL13409620 | 0.92 | RELA (0.81) | CYP1A1CYP1B1ESR1PTGS2NQO2 | |
| SCHEMBL631998 | 0.88 | RELA (0.81) | CYP1A1CYP1B1ESR1PTGS2NQO2 | |
| SCHEMBL13790336 | 0.88 | RELA (0.81) | CYP1A1CYP1B1ESR1PTGS2NQO2 | |
| SCHEMBL4881152 | 0.88 | RELA (0.81) | CYP1A1CYP1B1ESR1PTGS2NQO2 | |
| SCHEMBL699457 | 0.88 | RELA (0.81) | CYP1A1CYP1B1ESR1PTGS2NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292512-A1 | Methylated Curcumin-Resveratrol Hybrid Molecules for Treating Cancer | DEPUY SPINE, LLC | 2010-11-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292512-A1 | Methylated Curcumin-Resveratrol Hybrid Molecules for Treating Cancer | DNMT1, MECP2, BMI1 | CYP1A1 1164/4885CYP1B1 1454/4885ESR1 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.