Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 6/20 | 1.00 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 1.00 |
| ▸ | ESR1 | P03372 | 4/20 | 1.00 |
| ▸ | NQO2 | P16083 | 4/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 3/20 | 1.00 |
| ▸ | AHR | P35869 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 1.00 |
| ▸ | ABL1 | P00519 | 2/20 | 1.00 |
| ▸ | TTR | P02766 | 2/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 2/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 2/20 | 1.00 |
| ▸ | BCR | P11274 | 2/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 2/20 | 1.00 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 1.00 |
| ▸ | TUBB4A | P04350 | 1/20 | 1.00 |
| ▸ | TUBB | P07437 | 1/20 | 1.00 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 1.00 |
| ▸ | TUBA1B | P68363 | 1/20 | 1.00 |
| ▸ | TUBA4A | P68366 | 1/20 | 1.00 |
| ▸ | TUBB4B | P68371 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trismethoxyresveratrol SCHEMBL918739 | 1.00 | CYP1A1 (1.00) | CYP1A1CYP1B1ESR1NQO2PTGS2 | |
| Trismethoxyresveratrol SCHEMBL918740 | 1.00 | CYP1A1 (1.00) | CYP1A1CYP1B1ESR1NQO2PTGS2 | |
| SCHEMBL13443549 | 0.95 | CYP1A1 (0.91) | CYP1A1CYP1B1ESR1NQO2PTGS2 | |
| SCHEMBL3758141 | 0.95 | CYP1A1 (0.91) | CYP1A1CYP1B1ESR1NQO2PTGS2 | |
| SCHEMBL5809462 | 0.91 | CYP1A1 (0.84) | CYP1A1CYP1B1ESR1NQO2PTGS2 | |
| SCHEMBL5809455 | 0.91 | CYP1A1 (0.84) | CYP1A1CYP1B1ESR1NQO2PTGS2 | |
| SCHEMBL9177232 | 0.91 | TUBB1 (0.83) | CYP1A1CYP1B1ESR1NQO2PTGS2 | |
| SCHEMBL13790336 | 0.88 | RELA (0.81) | CYP1A1CYP1B1ESR1NQO2PTGS2 | |
| SCHEMBL1743365 | 0.88 | CYP1A1 (1.00) | CYP1A1CYP1B1ESR1NQO2PTGS2 | |
| SCHEMBL4881152 | 0.88 | RELA (0.81) | CYP1A1CYP1B1ESR1NQO2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859615-B2 | Compounds, compositions and methods for reducing toxicity and treating or preventing diseases | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-10-14 | — | — | US | claimed |
| CN-102215840-B | Compounds, compositions and methods for reducing toxicity and treating or preventing diseases | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-10-08 | — | — | CN | claimed |
| US-20120178704-A1 | PREVENTION AND TREATMENT OF COLON CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-07-12 | — | — | US | claimed |
| US-20110312904-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING TOXICITY AND TREATING OR PREVENTING DISEASES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2011-12-22 | — | — | US | claimed |
| EP-2331093-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING TOXICITY AND TREATING OR PREVENTING DISEASES | The Trustees of Columbia University in the City of New York (US) | 2011-06-15 | — | — | EP | claimed |
| US-20110124690-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER OR A NEUROTROPHIC DISORDER | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-05-26 | — | — | US | claimed |
| WO-2010025272-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING TOXICITY AND TREATING OR PREVENTING DISEASES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-03-04 | — | — | WO | claimed |
| WO-2009105123-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING DISEASES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-08-27 | — | — | WO | claimed |
| WO-2008103916-A2 | COMPOSITIONS AND METHODS FOR TREATING CANCER OR A NEUROTROPHIC DISORDER | THE TRUSTEES OF COLUMBIA UNIVERISTY IN THE CITY OF NEW YORK (US) | 2008-08-28 | — | — | WO | claimed |
| WO-2008070872-A1 | PREVENTION AND TREATMENT OF COLON CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2008-06-12 | — | — | WO | claimed |
| WO-2003031381-A2 | SYNTHESIS OF (Z)-3,5,4'-TRIMETHOXYSTILBENE, AND USE THEREOF | UNIVERSITE LOUIS PASTEUR (FR) | 2003-04-17 | — | — | WO | claimed |
| US-12404221-B2 | Methods of arene alkenylation | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2025-09-02 | — | — | US | disclosed |
| US-20250127890-A1 | COMPOSITIONS AND METHODS FOR TREATING CORONAVIRUS INFECTIOUS DISEASE-19 (COVID-19) | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2025-04-24 | — | — | US | disclosed |
| US-20250084103-A1 | COMPOUNDS, CONJUGATES, AND COMPOSITIONS OF EPIPOLYTHIODIKETOPIPERAZINES AND POLYTHIODIKETOPIPERAZINES AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-03-13 | — | — | US | disclosed |
| US-12180228-B2 | Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-12-31 | — | — | US | disclosed |
| WO-2003031381-A2 | SYNTHESIS OF (Z)-3,5,4'-TRIMETHOXYSTILBENE, AND USE THEREOF | UNIVERSITE LOUIS PASTEUR (FR) | 2003-04-17 | — | — | WO | disclosed |
| WO-2003031381-A2 | SYNTHESIS OF (Z)-3,5,4'-TRIMETHOXYSTILBENE, AND USE THEREOF | UNIVERSITE LOUIS PASTEUR (FR) | 2003-04-17 | — | — | WO | disclosed |
| WO-2003031381-A2 | SYNTHESIS OF (Z)-3,5,4'-TRIMETHOXYSTILBENE, AND USE THEREOF | UNIVERSITE LOUIS PASTEUR (FR) | 2003-04-17 | — | — | WO | disclosed |
| US-5430062-A | Combretastatin analogues; inhibition of tubulin polymerization and colchicine binding; antitumor,-mitotic and -neoplastic agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1993023357-A1 | STILBENE DERIVATIVES AS ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312904-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING TOXICITY AND TREATING OR PREVENTING DISEASES | TUBA1C, TUBB1, TOP1 | CYP1A1 1266/4885CYP1B1 1897/4885ESR1 4109/4885 |
| US-20120178704-A1 | PREVENTION AND TREATMENT OF COLON CANCER | APC, SI, NFKBIA | CYP1A1 1123/4885CYP1B1 1133/4885ESR1 2698/4885 |
| US-20250084103-A1 | COMPOUNDS, CONJUGATES, AND COMPOSITIONS OF EPIPOLYTHIODIKETOPIPERAZINES AND POLYTHIODIKETOPIPERAZINES AND USES THEREOF | DNPEP, DHPS, NPEPPS | CYP1A1 832/4885CYP1B1 248/4885ESR1 2013/4885 |
| US-12404221-B2 | Methods of arene alkenylation | CYBB, CBR3, AHR | CYP1A1 90/4885CYP1B1 62/4885ESR1 179/4885 |
| US-20110124690-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER OR A NEUROTROPHIC DISORDER | BDNF, NGF, NTRK2 | CYP1A1 4875/4885CYP1B1 4861/4885ESR1 4561/4885 |
| US-12180228-B2 | Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof | DNPEP, DHPS, NPEPPS | CYP1A1 832/4885CYP1B1 248/4885ESR1 2013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.