Sugi Predict

Sugi Predict / Compounds / SCHEMBL375892

SCHEMBL375892

SCHEMBL375892

CCCCCCCCCCCCCCCCCCO[Si](CCS)(OCCCCCCCCCCCCCCCCCC)OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LPAR3 Q9UBY5 6/20 0.38
▸ LPAR2 Q9HBW0 5/20 0.38
▸ THRB P10828 2/20 0.35
▸ TSHR P16473 1/20 0.35
▸ MEN1 O00255 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ CA1 P00915 8/20 0.33
▸ CA2 P00918 8/20 0.33
▸ CA9 Q16790 7/20 0.33
▸ CA12 O43570 3/20 0.33
▸ CA7 P43166 3/20 0.33
▸ CA14 Q9ULX7 3/20 0.33
▸ LPAR1 Q92633 2/20 0.33
▸ CA3 P07451 2/20 0.33
▸ CA4 P22748 2/20 0.33
▸ CA6 P23280 2/20 0.33
▸ CA5A P35218 2/20 0.33
▸ CA5B Q9Y2D0 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375712 1.00 LPAR3 (0.38) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL375285 1.00 LPAR3 (0.38) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL375703 1.00 LPAR3 (0.38) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL375349 1.00 LPAR3 (0.38) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL375747 1.00 LPAR3 (0.38) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL11785281 0.98 LPAR3 (0.34) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL477479 0.91 ADRB2 (0.35) TSHR
SCHEMBL2334553 0.89 LPAR3 (0.36) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL4541328 0.89 LPAR3 (0.36) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL374484 0.89 LPAR3 (0.36) LPAR3LPAR2THRBTSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7518009-B2 Process for preparing mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2009-04-14 — — US claimed
US-20060252952-A1 Process for preparing mercaptoorganyl (alkoxysilanes) DEGUSSA AG (DE) 2006-11-09 — — US claimed
US-12139635-B2 Coatings for waterproofing electronic components HENKEL AG & CO. KGAA (DE) 2024-11-12 — — US disclosed
US-20220002559-A1 COATINGS FOR WATERPROOFING ELECTRONIC COMPONENTS HENKEL AG & CO. KGAA (DE) 2022-01-06 — — US disclosed
WO-2020197963-A1 COATINGS FOR WATERPROOFING ELECTRONIC COMPONENTS HENKEL AG & CO. KGAA (DE) 2020-10-01 — — WO disclosed
US-20140005432-A1 PROCESS FOR PREPARING ORGANOSILANES EVONIK DEGUSSA GMBH (DE) 2014-01-02 — — US disclosed
EP-2408785-A1 PROCESS FOR PREPARING ORGANOSILANES Evonik Degussa GmbH (DE) 2012-01-25 — — EP disclosed
WO-2010105434-A1 PROCESS FOR PREPARING ORGANOSILANES EVONIK DEGUSSA GMBH (DE) 2010-09-23 — — WO disclosed
US-7518009-B2 Process for preparing mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2009-04-14 — — US disclosed
US-7501534-B2 Process for the preparation of organosilanes DEGUSSA AG (DE) 2009-03-10 — — US disclosed
US-7339067-B2 Process for producing mercaptoorganyl (alkoxysilane) EVONIK DEGUSSA GMBH (DE) 2008-03-04 — — US disclosed
EP-1538152-B1 Process for the preparation of (mercaptoorganyl)-alkoxysilanen DEGUSSA (DE) 2006-03-22 — — EP disclosed
EP-1634884-A1 Process for preparing mercaptoorganyl alkoxy silanes Degussa GmbH (DE) 2006-03-15 — — EP disclosed
US-20060052622-A1 Process for the preparation of mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2006-03-09 — — US disclosed
US-20060052621-A1 Process for producing mercaptoorganyl (alkoxysilane) EVONIK DEGUSSA GMBH (DE) 2006-03-09 — — US disclosed
US-6995280-B2 Process for preparing (mercaptoorganyl)alkoxysilanes DEGUSSA AG (DE) 2006-02-07 — — US disclosed
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 — — US disclosed
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 — — US disclosed
EP-1538152-A1 Process for the preparation of (mercaptoorganyl)-alkoxysilanen Degussa AG (DE) 2005-06-08 — — EP disclosed
EP-1529782-A1 Process for preparing mercaptoorganyl alkoxy silanes Degussa AG (DE) 2005-05-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes ADH1C, ADH1A, MPST LPAR3 3214/4885LPAR2 2800/4885THRB 4696/4885
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes MPST, ADH1A, ADH1C LPAR3 2985/4885LPAR2 2555/4885THRB 4640/4885
US-20140005432-A1 PROCESS FOR PREPARING ORGANOSILANES MPST, STS, CYP2S1 LPAR3 3000/4885LPAR2 1773/4885THRB 3983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.