Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 14/20 | 0.65 |
| ▸ | FAAH | O00519 | 5/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289960 | 0.89 | MGLL (0.52) | MGLLFAAHMAPK1HSP90AA1PKM | |
| SCHEMBL458382 | 0.89 | MGLL (0.52) | MGLLFAAHMAPK1HSP90AA1PKM | |
| SCHEMBL8467655 | 0.89 | HSP90AA1 (0.64) | MGLLFAAHMAPK1HSP90AA1PKM | |
| SCHEMBL5150580 | 0.89 | MGLL (0.52) | MGLLFAAHMAPK1PKMNPSR1 | |
| SCHEMBL3665727 | 0.87 | MGLL (0.65) | MGLLFAAHMAPK1HSP90AA1PKM | |
| SCHEMBL27650867 | 0.85 | MGLL (0.50) | MGLLFAAHMAPK1HSP90AA1PKM | |
| SCHEMBL3672504 | 0.82 | MGLL (0.71) | MGLLFAAHMAPK1HSP90AA1PKM | |
| SCHEMBL95324 | 0.81 | MGLL (1.00) | MGLLFAAHMAPK1HSP90AA1PKM | |
| SCHEMBL7062361 | 0.80 | MGLL (0.61) | MGLLFAAHMAPK1HSP90AA1PKM | |
| SCHEMBL28774595 | 0.78 | MEN1 (0.62) | MGLLFAAHMAPK1HSP90AA1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821300-A | MONOMERS INCLUDE ORGANOTIN-CONTAINING (METH)ACRYLATES AND N-SUBSTITUTED MALEIMIDES | WITCO GMBH (DE) | 1998-10-13 | — | — | US | claimed |
| EP-0841353-A1 | Process for the preparation of polymeric binders and their application as antifouling paint | Witco GmbH (DE) | 1998-05-13 | — | — | EP | claimed |
| CN-114574223-A | Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal element | JSR株式会社 | 2022-06-03 | — | — | CN | disclosed |
| CN-107045064-A | A kind of pre-treating method of polypeptide based on derivatization in plasma sample | 中国药科大学 | 2017-08-15 | — | — | CN | disclosed |
| WO-2012117367-A1 | PROBE AND PRIMER SEQUENCES FOR DETECTION OF HEPATITIS B VIRUS BY REAL-TIME PCR, PCR REACTION MIXTURE AND KITS THEREOF. | BIGTEC PRIVATE LIMITED (IN) | 2012-09-07 | — | — | WO | disclosed |
| WO-2012095714-A1 | PROBES AND PRIMERS FOR DETECTING TYPHOID | BIGTEC PRIVATE LIMITED (IN) | 2012-07-19 | — | — | WO | disclosed |
| US-20100305121-A1 | NOVEL ANTAGONISTS OF THE HUMAN FATTY ACID SYNTHASE THIOESTERASE | BURHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100305121-A1 | NOVEL ANTAGONISTS OF THE HUMAN FATTY ACID SYNTHASE THIOESTERASE | BURHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100305121-A1 | NOVEL ANTAGONISTS OF THE HUMAN FATTY ACID SYNTHASE THIOESTERASE | BURHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-12-02 | — | — | US | disclosed |
| US-20070203236-A1 | NOVEL ANTAGONISTS OF THE HUMAN FATTY ACID SYNTHASE THIOESTERASE | UNITED STATES GOVERNMENT | 2007-08-30 | — | — | US | disclosed |
| US-20070203236-A1 | NOVEL ANTAGONISTS OF THE HUMAN FATTY ACID SYNTHASE THIOESTERASE | UNITED STATES GOVERNMENT | 2007-08-30 | — | — | US | disclosed |
| US-20070203236-A1 | NOVEL ANTAGONISTS OF THE HUMAN FATTY ACID SYNTHASE THIOESTERASE | UNITED STATES GOVERNMENT | 2007-08-30 | — | — | US | disclosed |
| EP-1190244-B1 | METHOD OF PRODUCING MONOLITHIC SUPPORT MATERIALS | BUCHMEISER MICHAEL RUDOLF (AT) | 2003-02-26 | — | — | EP | disclosed |
| EP-1190244-A1 | METHOD OF PRODUCING MONOLITHIC SUPPORT MATERIALS | MERCK PATENT GmbH (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000073782-A1 | METHOD OF PRODUCING MONOLITHIC SUPPORT MATERIALS | MERCK PATENT GMBH (DE) | 2000-12-07 | — | — | WO | disclosed |
| US-5821300-A | MONOMERS INCLUDE ORGANOTIN-CONTAINING (METH)ACRYLATES AND N-SUBSTITUTED MALEIMIDES | WITCO GMBH (DE) | 1998-10-13 | — | — | US | disclosed |
| EP-0841353-A1 | Process for the preparation of polymeric binders and their application as antifouling paint | Witco GmbH (DE) | 1998-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203236-A1 | NOVEL ANTAGONISTS OF THE HUMAN FATTY ACID SYNTHASE THIOESTERASE | FADS2, ACOT7, FADS1 | MGLL 316/4885FAAH 85/4885MAPK1 3195/4885 |
| US-20100305121-A1 | NOVEL ANTAGONISTS OF THE HUMAN FATTY ACID SYNTHASE THIOESTERASE | FADS2, ACOT7, FADS1 | MGLL 316/4885FAAH 85/4885MAPK1 3195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.